Does <SUP>18</SUP>F-FDG Positron Emission Tomography-Computed Tomography Have a Role in Initial Staging of Hepatocellular Carcinoma?
DC Field | Value | Language |
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dc.contributor.author | Cho, Yuri | - |
dc.contributor.author | Lee, Dong Hyeon | - |
dc.contributor.author | Lee, Yun Bin | - |
dc.contributor.author | Lee, Minjong | - |
dc.contributor.author | Yoo, Jeong-ju | - |
dc.contributor.author | Choi, Won-Mook | - |
dc.contributor.author | Cho, Young Youn | - |
dc.contributor.author | Paeng, Jin Chul | - |
dc.contributor.author | Kang, Keon Wook | - |
dc.contributor.author | Chung, June-Key | - |
dc.contributor.author | Yu, Su Jong | - |
dc.contributor.author | Lee, Jeong-Hoon | - |
dc.contributor.author | Yoon, Jung-Hwan | - |
dc.contributor.author | Lee, Hyo-Suk | - |
dc.contributor.author | Kim, Yoon Jun | - |
dc.date.accessioned | 2024-01-09T17:02:52Z | - |
dc.date.available | 2024-01-09T17:02:52Z | - |
dc.date.issued | 2014-08 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70843 | - |
dc.description.abstract | Background and Aim: The utility of fluorine-18 fluorodeoxyglucose (F-18-FDG) positron emission tomography-computed tomography (PET/CT) in initial staging of hepatocellular carcinoma (HCC) has yet to be fully explored. We assessed the usefulness of F-18-FDG PET/CT in initial staging of HCC. Methods: A total of 457 consecutive patients initially diagnosed with HCC at Seoul National University Hospital between 2006 and 2012 were evaluated retrospectively to assess the impact of F-18-FDG PET/CT on staging and compliancy with Milan criteria, relative to dynamic CT of liver and chest x-ray. Results: Seven among the 457 patients studied showed a shift in Barcelona Clinic Liver Cancer [BCLC] stage (A -> C: 6 patients; B -> C: 1 patient) and 5 patients who had originally met Milan criteria no longer qualified. F-18-FDG PET/CT had value in initial staging of early (stage A) or intermediate (stage B) HCC, as determined by dynamic CT of liver and BCLC or AJCC classifications, whereas BCLC stage 0 and stage C tumors were unchanged (P<0.001). F-18-FDG PET/CT disclosed additional metastases in patients with American Joint Committee on Cancer [AJCC] T2 (2.7%), T3a (5.3%), and T3b (4.8%) classifications. Conclusions: In initial staging of HCC, F-18-FDG PET/CT provided additional information, impacting the patients with BCLC (stages A and B) and AJCC (T2 and T3) classifications. Its use might be thus appropriate for these patient subsets, especially if hepatic resection or liver transplantation is planned. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.title | Does <SUP>18</SUP>F-FDG Positron Emission Tomography-Computed Tomography Have a Role in Initial Staging of Hepatocellular Carcinoma? | - |
dc.type | Article | - |
dc.identifier.doi | 10.1371/journal.pone.0105679 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.9, no.8 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000340952200069 | - |
dc.identifier.scopusid | 2-s2.0-84937487555 | - |
dc.citation.number | 8 | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 9 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | LIVER-TRANSPLANT CANDIDATES | - |
dc.subject.keywordPlus | EXTRAHEPATIC METASTASES | - |
dc.subject.keywordPlus | F-18-FLUORODEOXYGLUCOSE UPTAKE | - |
dc.subject.keywordPlus | PET | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | FLUORINE-18-FLUORODEOXYGLUCOSE | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | SORAFENIB | - |
dc.subject.keywordPlus | RESECTION | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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