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Does <SUP>18</SUP>F-FDG Positron Emission Tomography-Computed Tomography Have a Role in Initial Staging of Hepatocellular Carcinoma?

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dc.contributor.authorCho, Yuri-
dc.contributor.authorLee, Dong Hyeon-
dc.contributor.authorLee, Yun Bin-
dc.contributor.authorLee, Minjong-
dc.contributor.authorYoo, Jeong-ju-
dc.contributor.authorChoi, Won-Mook-
dc.contributor.authorCho, Young Youn-
dc.contributor.authorPaeng, Jin Chul-
dc.contributor.authorKang, Keon Wook-
dc.contributor.authorChung, June-Key-
dc.contributor.authorYu, Su Jong-
dc.contributor.authorLee, Jeong-Hoon-
dc.contributor.authorYoon, Jung-Hwan-
dc.contributor.authorLee, Hyo-Suk-
dc.contributor.authorKim, Yoon Jun-
dc.date.accessioned2024-01-09T17:02:52Z-
dc.date.available2024-01-09T17:02:52Z-
dc.date.issued2014-08-
dc.identifier.issn1932-6203-
dc.identifier.urihttps://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70843-
dc.description.abstractBackground and Aim: The utility of fluorine-18 fluorodeoxyglucose (F-18-FDG) positron emission tomography-computed tomography (PET/CT) in initial staging of hepatocellular carcinoma (HCC) has yet to be fully explored. We assessed the usefulness of F-18-FDG PET/CT in initial staging of HCC. Methods: A total of 457 consecutive patients initially diagnosed with HCC at Seoul National University Hospital between 2006 and 2012 were evaluated retrospectively to assess the impact of F-18-FDG PET/CT on staging and compliancy with Milan criteria, relative to dynamic CT of liver and chest x-ray. Results: Seven among the 457 patients studied showed a shift in Barcelona Clinic Liver Cancer [BCLC] stage (A -&gt; C: 6 patients; B -&gt; C: 1 patient) and 5 patients who had originally met Milan criteria no longer qualified. F-18-FDG PET/CT had value in initial staging of early (stage A) or intermediate (stage B) HCC, as determined by dynamic CT of liver and BCLC or AJCC classifications, whereas BCLC stage 0 and stage C tumors were unchanged (P&lt;0.001). F-18-FDG PET/CT disclosed additional metastases in patients with American Joint Committee on Cancer [AJCC] T2 (2.7%), T3a (5.3%), and T3b (4.8%) classifications. Conclusions: In initial staging of HCC, F-18-FDG PET/CT provided additional information, impacting the patients with BCLC (stages A and B) and AJCC (T2 and T3) classifications. Its use might be thus appropriate for these patient subsets, especially if hepatic resection or liver transplantation is planned.-
dc.language영어-
dc.language.isoENG-
dc.publisherPUBLIC LIBRARY SCIENCE-
dc.titleDoes &lt;SUP&gt;18&lt;/SUP&gt;F-FDG Positron Emission Tomography-Computed Tomography Have a Role in Initial Staging of Hepatocellular Carcinoma?-
dc.typeArticle-
dc.identifier.doi10.1371/journal.pone.0105679-
dc.identifier.bibliographicCitationPLOS ONE, v.9, no.8-
dc.description.isOpenAccessY-
dc.identifier.wosid000340952200069-
dc.identifier.scopusid2-s2.0-84937487555-
dc.citation.number8-
dc.citation.titlePLOS ONE-
dc.citation.volume9-
dc.type.docTypeArticle-
dc.publisher.location미국-
dc.subject.keywordPlusLIVER-TRANSPLANT CANDIDATES-
dc.subject.keywordPlusEXTRAHEPATIC METASTASES-
dc.subject.keywordPlusF-18-FLUORODEOXYGLUCOSE UPTAKE-
dc.subject.keywordPlusPET-
dc.subject.keywordPlusRECURRENCE-
dc.subject.keywordPlusCT-
dc.subject.keywordPlusFLUORINE-18-FLUORODEOXYGLUCOSE-
dc.subject.keywordPlusMANAGEMENT-
dc.subject.keywordPlusSORAFENIB-
dc.subject.keywordPlusRESECTION-
dc.relation.journalResearchAreaScience &amp; Technology - Other Topics-
dc.relation.journalWebOfScienceCategoryMultidisciplinary Sciences-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
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