Neurological Pupil Index as an Indicator of Neurological Worsening in Large Hemispheric Strokes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Tae Jung | - |
dc.contributor.author | Park, Soo-Hyun | - |
dc.contributor.author | Jeong, Hae-Bong | - |
dc.contributor.author | Ha, Eun Jin | - |
dc.contributor.author | Cho, Won Sang | - |
dc.contributor.author | Kang, Hyun-Seung | - |
dc.contributor.author | Kim, Jung Eun | - |
dc.contributor.author | Ko, Sang-Bae | - |
dc.date.accessioned | 2024-01-09T17:33:51Z | - |
dc.date.available | 2024-01-09T17:33:51Z | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 1541-6933 | - |
dc.identifier.issn | 1556-0961 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70880 | - |
dc.description.abstract | Background/Objective Cerebral herniation due to brain edema is the major cause of neurological worsening in patients suffering large hemispheric strokes. In this study, we investigated whether quantitative pupillary response could help identify the neurological worsening due to brain swelling in patients with large hemispheric strokes. Methods Quantitative pupillary assessment using an automated pupillometer (NPi-100) was performed between April 2017 and August 2019 for patients suffering large hemispheric strokes. Consecutive pupillary responses were measured every 2 or 4 h as a part of routine clinical care. We compared the mean neurological pupil index (NPi) values, NPi value at the time of neurological deterioration, and percentage change in NPi from the immediate previous value between patients with and without neurological worsening. Results In this study, 2442 quantitative pupillary assessments were performed (n = 30; mean age, 67.9 years; males, 60.0%). Among the included patients, 10 (33.3%) experienced neurological worsening. Patients with neurological worsening had a significantly lower mean value of NPi and a sudden decrease in the NPi value as compared to those without neurological worsening during the whole monitoring period (3.88 +/- 0.65 vs. 4.45 +/- 0.46, P < 0.001; and 29.5% vs. 11.1%, P = 0.006, respectively). All patients with NPi values below 2.8 showed neurological deterioration. Conclusions Quantitative monitoring of the pupillary response using an automated pupillometer could be a useful and noninvasive tool for detecting neurological deterioration due to cerebral edema in large hemispheric stroke patients. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | HUMANA PRESS INC | - |
dc.title | Neurological Pupil Index as an Indicator of Neurological Worsening in Large Hemispheric Strokes | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s12028-020-00936-0 | - |
dc.identifier.bibliographicCitation | NEUROCRITICAL CARE, v.33, no.2, pp 575 - 581 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000516453200004 | - |
dc.identifier.scopusid | 2-s2.0-85091265292 | - |
dc.citation.endPage | 581 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 575 | - |
dc.citation.title | NEUROCRITICAL CARE | - |
dc.citation.volume | 33 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Neurological pupil index | - |
dc.subject.keywordAuthor | Neurological worsening | - |
dc.subject.keywordAuthor | Large hemispheric stroke | - |
dc.subject.keywordPlus | MIDDLE CEREBRAL-ARTERY | - |
dc.subject.keywordPlus | TRAUMATIC BRAIN-INJURY | - |
dc.subject.keywordPlus | QUANTITATIVE PUPILLOMETRY | - |
dc.subject.keywordPlus | TRANSTENTORIAL HERNIATION | - |
dc.subject.keywordPlus | INTRACRANIAL-PRESSURE | - |
dc.subject.keywordPlus | DECOMPRESSIVE SURGERY | - |
dc.subject.keywordPlus | MALIGNANT INFARCTION | - |
dc.subject.keywordPlus | MIDLINE SHIFT | - |
dc.subject.keywordPlus | DETERIORATION | - |
dc.subject.keywordPlus | MULTICENTER | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Critical Care Medicine | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.