Diagnostic accuracy of adding copeptin to cardiac troponin for non-ST-elevation myocardial infarction: A systematic review and meta-analysis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Hyungoo | - |
dc.contributor.author | Jang, Bo-Hyoung | - |
dc.contributor.author | Lim, Tae Ho | - |
dc.contributor.author | Lee, Juncheol | - |
dc.contributor.author | Kim, Wonhee | - |
dc.contributor.author | Cho, Youngsuk | - |
dc.contributor.author | Ahn, Chiwon | - |
dc.contributor.author | Choi, Kyu-Sun | - |
dc.date.accessioned | 2024-01-18T05:01:17Z | - |
dc.date.available | 2024-01-18T05:01:17Z | - |
dc.date.issued | 2018-07 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71047 | - |
dc.description.abstract | Introduction This study aimed to determine the diagnostic accuracy of adding copeptin to cardiac troponin (cTn) on admission to the emergency department (ED) for non-ST elevation myocardial infarction (NSTEMI) compared to cTn alone. Materials and methods A literature search of MEDLINE, EMBASE, and the Cochrane Library was performed (search date: April 13, 2018). Primary studies were included if they accurately reported on patients with symptoms suggestive of acute myocardial infarction and measured both cTn alone and cTn with copeptin upon admission to the ED. The patients with evidence of ST elevation myocardial infarction were excluded. To assess the risk of bias for the included studies, the QUADAS-2 tool was used. Results The study participants included a total of 7,998 patients from 14 observational studies. The addition of copeptin to cTn significantly improved the sensitivity (0.81 [0.74 to 0.87] vs. 0.92 [0.89 to 0.95], respectively, p < 0.001) and negative predictive value (0.96 [0.95 to 0.98] vs. 0.98 [0.96 to 0.99], respectively, p < 0.001) at the expense of lower specificity (0.88 [0.80 to 0.97] vs. 0.57 [0.49 to 0.65], respectively, p < 0.001) compared to cTn alone. Furthermore, adding copeptin to cTn showed significantly lower diagnostic accuracy for NSTEMI compared to cTn alone (0.91[0.90 to 0.92] vs. 0.85 [0.83 to 0.86], respectively, p < 0.001). Conclusions Adding copeptin to cTn improved the sensitivity and negative predictive value for the diagnosis of NSTEMI compared to cTn alone. Thus, adding copeptin to cTn might help to screen NSTEMI early upon admission to the ED. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.title | Diagnostic accuracy of adding copeptin to cardiac troponin for non-ST-elevation myocardial infarction: A systematic review and meta-analysis | - |
dc.type | Article | - |
dc.identifier.doi | 10.1371/journal.pone.0200379 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.13, no.7 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000437809500103 | - |
dc.identifier.scopusid | 2-s2.0-85049509616 | - |
dc.citation.number | 7 | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 13 | - |
dc.type.docType | Review | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | ACUTE CORONARY SYNDROME | - |
dc.subject.keywordPlus | HIGH-SENSITIVITY TROPONIN | - |
dc.subject.keywordPlus | EARLY RULE-OUT | - |
dc.subject.keywordPlus | INCREMENTAL VALUE | - |
dc.subject.keywordPlus | RAPID RULE | - |
dc.subject.keywordPlus | UNIVERSAL DEFINITION | - |
dc.subject.keywordPlus | ASSAYS | - |
dc.subject.keywordPlus | BIOMARKERS | - |
dc.subject.keywordPlus | IMPACT | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.