Prognostic effect of sex according to shock severity in patients with acute myocardial infarction complicated by cardiogenic shock
DC Field | Value | Language |
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dc.contributor.author | Kim, Yeji | - |
dc.contributor.author | Jang, Woo Jin | - |
dc.contributor.author | Park, Ik hyun | - |
dc.contributor.author | Oh, Ju Hyeon | - |
dc.contributor.author | Yang, Jeong Hoon | - |
dc.contributor.author | Gwon, Hyeon-Cheol | - |
dc.contributor.author | Ahn, Chul-Min | - |
dc.contributor.author | Yu, Cheol Woong | - |
dc.contributor.author | Kim, Hyun-Joong | - |
dc.contributor.author | Bae, Jang-Whan | - |
dc.contributor.author | Kwon, Sung Uk | - |
dc.contributor.author | Lee, Hyun-Jong | - |
dc.contributor.author | Lee, Wang Soo | - |
dc.contributor.author | Jeong, Jin-Ok | - |
dc.contributor.author | Park, Sang-Don | - |
dc.date.accessioned | 2024-01-22T04:30:21Z | - |
dc.date.available | 2024-01-22T04:30:21Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 1109-9666 | - |
dc.identifier.issn | 2241-5955 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71214 | - |
dc.description.abstract | Background: Sex disparities in cardiogenic shock (CS) treatment are controversial, and the prognostic implications of sex remain unclear in CS caused by acute myocardial infarction (AMI). Objectives: This study aimed to evaluate the prognostic effect of sex according to the severity of CS in patients undergoing percutaneous coronary intervention (PCI) for AMI complicated by CS. Methods: We assessed 695 patients from 12 tertiary centers in South Korea who underwent PCI for AMI complicated by CS, and analyzed outcomes by sex (female [n = 184] vs. male [n = 511]). We compared a 12-month patient-oriented composite endpoint (POCE, defined as a composite of all-cause mortality, myocardial infarction, re-hospitalization due to heart failure, and repeat revascularization) between the sexes, respective of SCAI shock stage C&D or E. Propensity score-matched analysis was performed to reduce bias. Results: We found that the female group was older and had higher vasoactive-inotropic and IABP-SHOCK II scores than the male group, with findings consistent across SCAI shock stages. During the 12-month follow-up period, multivariate analysis revealed no significant differences in POCE (HR 1.01, 95% CI 0.67–1.53, p = 0.963 for SCAI stage C&D, HR 1.24, 95% CI 0.84–1.84, p = 0.286 for SCAI stage E) between females and males. After propensity score matching, the incidence of POCE (HR 1.47, 95% CI 0.79–2.72, p = 0.220 for SCAI stage C&D, HR 0.88, 95% CI 0.49–1.57, p = 0.665 for SCAI stage E) was similar between sexes. Conclusions: Sex does not appear to influence the risk of 12-month POCE in patients treated with PCI for CS caused by AMI, irrespective of shock severity. Clinical Trial Registration: ClinicalTrials.gov NCT02985008. RESCUE (REtrospective and prospective observational Study to investigate Clinical oUtcomes and Efficacy of left ventricular assist device for Korean patients with cardiogenic shock), NCT02985008, Registered December 5, 2016 - retrospectively and prospectively. IRB Information: This study was approved by the institutional review board of Samsung Medical Center (Reference number: 2016-03-130). © 2023 Hellenic Society of Cardiology | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Hellenic Cardiological Society | - |
dc.title | Prognostic effect of sex according to shock severity in patients with acute myocardial infarction complicated by cardiogenic shock | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.hjc.2023.11.007 | - |
dc.identifier.bibliographicCitation | Hellenic Journal of Cardiology | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85181812020 | - |
dc.citation.title | Hellenic Journal of Cardiology | - |
dc.type.docType | Article in press | - |
dc.publisher.location | 그리이스 | - |
dc.subject.keywordAuthor | Acute myocardial infarction | - |
dc.subject.keywordAuthor | Cardiogenic shock | - |
dc.subject.keywordAuthor | SCAI shock classification | - |
dc.subject.keywordAuthor | Sex | - |
dc.description.journalRegisteredClass | scopus | - |
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