Treatment Efficacy of Various Maneuvers for Lateral Canal Benign Paroxysmal Positional Vertigo With Apogeotropic Nystagmus: A Randomized Controlled Trial

Abstract

Objectives. The aim of this study was to determine the most effective treatment approach by comparing the impacts ofvarious otolith reduction techniques in patients with apogeotropic lateral semicircular canal benign paroxysmal posi-tional vertigo (LC-BPPV). Methods. We performed a multicenter randomized prospective study from January to December 2015, involving 72 con-secutive patients with apogeotropic LC-BPPV. The patients were divided into three treatment groups: therapeutichead-shaking (group A), the Gufoni-Appiani maneuver (group B), and the cupulolith repositioning maneuver (CuRM;group C). Each group underwent evaluation and treatment up to the fourth week. Treatment success was defined asthe disappearance of positional vertigo and nystagmus. Results. This study included 72 patients (49 male and 23 female), with a mean (±standard deviation) age of 55.4±13.5 years. The mean duration of vertigo experienced prior to treatment was 3.9±4.4 days. The mean latency and duration ofnystagmus were 2.7±3.0 seconds and 47.9±15.8 seconds, respectively. The overall treatment frequency was 2.0±0.9. The number of treatments differed significantly among the three groups (P <0.05). After 4 weeks, the success ratesfor groups A, B, and C were 90.5%, 92.3%, and 100%, respectively. No significant difference was observed in thesuccess rate across treatment methods and periods (P >0.05). However, CuRM was the only method with a 100%treatment success rate. Conclusion. While no clear difference was observed among the three treatments for LC-BPPV, CuRM was found to be su-perior to the other approaches in the long term.