Cytarabine에 의한 지연성 아나필락시스에 대한 성공적인 탈감작 치료 1예open accessSuccessful desensitization for cytarabine induced anaphylaxis
- Authors
- 이현우; 박재용; 문준호; 박경택; 박한기; 강혜련
- Issue Date
- Nov-2014
- Publisher
- 대한 소아알레르기 호흡기학회
- Keywords
- Anaphylaxis; Cytarabine; Immunologic desensitization
- Citation
- Allergy Asthma & Respiratory Disease, v.2, no.5, pp 394 - 397
- Pages
- 4
- Journal Title
- Allergy Asthma & Respiratory Disease
- Volume
- 2
- Number
- 5
- Start Page
- 394
- End Page
- 397
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71630
- ISSN
- 2288-0402
2288-0410
- Abstract
- Cytarabine is a very important chemotherapeutic agent for leukemia and lymphoma patients and is prescribed more frequently than before. Cytarabine-induced delayed-onset hypersensitivity may rarely present as non-IgE mediated anaphylaxis. However, we do not know yet whether desensitization therapy in adults may be effective in cytarabine-induced delayed-onset anaphylaxis. A 78-year-old woman who was diagnosed with acute myeloblastic leukemia had chemotherapy including cytarabine. In spite of premedication with hydrocortisone and chlorpheniramine, the patient had anaphylaxis a few hours after cytarabine infusion. We decided to perform desensitization therapy. After desensitization therapy using a newly designed protocol, the patient was tolerable to cytarabine infusion without hypotension or high fever. Desensitization therapy was successfully performed on an adult patient with delayed-onset anaphylaxis caused by cytarabine.
- Files in This Item
-
- Appears in
Collections - ETC > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71630)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.