Distribution of emm genotypes in group A streptococcus isolates of Korean children from 2012 to 2019
DC Field | Value | Language |
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dc.contributor.author | Cho, You Na | - |
dc.contributor.author | Park, Su Eun | - |
dc.contributor.author | Cho, Eun Young | - |
dc.contributor.author | Cho, Hye Kyung | - |
dc.contributor.author | Park, Ji Young | - |
dc.contributor.author | Kang, Hyun-Mi | - |
dc.contributor.author | Yun, Ki Wook | - |
dc.contributor.author | Choi, Eun Hwa | - |
dc.contributor.author | Lee, Hyunju | - |
dc.date.accessioned | 2024-02-08T05:30:45Z | - |
dc.date.available | 2024-02-08T05:30:45Z | - |
dc.date.issued | 2022-08 | - |
dc.identifier.issn | 1684-1182 | - |
dc.identifier.issn | 1995-9133 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/71873 | - |
dc.description.abstract | Objectives: Changes in the epidemiology of group A streptococcus (GAS) infection is related to emm genotype. We studied the distribution of emm genotypes and their antibiotic susceptibility among Korean children.Methods: Isolates from children with GAS infection between 2012 and 2019 were collected. emm typing and cluster analysis was performed according to the Centers for Disease Control emm cluster classification. Antimicrobial susceptibility was tested using the E-test and resis-tance genes were analyzed for macrolide resistant phenotypes.Results: Among 169 GAS isolates, 115 were from children with scarlet fever. Among invasive isolates, emm1 (6/22, 27.3%), emm12 (4/22, 18.2%), and emm4 (4/22, 18.2%) were most com-mon. In scarlet fever, although emm4 (38/115, 33.0%) was the most prevalent throughout the study period, emm4 was replaced by emm3 (28/90, 31.1%) during an outbreak in 2017-2018. Among all isolates, only 2 (1.2%) exhibited erythromycin resistance and harbored both ermA and ermB genes.Conclusions: In this analysis of GAS isolated from Korean children, emm1 was the most preva-lent in invasive infection. In scarlet fever, emm4 was prevalent throughout the study period, with an increase in emm3 during 2017-2018. GAS isolates during 2012-2019 demonstrated low erythromycin resistance.Copyright (c) 2022, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER TAIWAN | - |
dc.title | Distribution of emm genotypes in group A streptococcus isolates of Korean children from 2012 to 2019 | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jmii.2022.05.001 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, v.55, no.4, pp 671 - 677 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000862802900012 | - |
dc.identifier.scopusid | 2-s2.0-85130562360 | - |
dc.citation.endPage | 677 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 671 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | - |
dc.citation.volume | 55 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대만 | - |
dc.subject.keywordAuthor | Streptococcus pyogenes | - |
dc.subject.keywordAuthor | Molecular epidemiology | - |
dc.subject.keywordAuthor | Scarlet fever | - |
dc.subject.keywordAuthor | Child | - |
dc.subject.keywordAuthor | Streptococcal M protein | - |
dc.subject.keywordPlus | SCARLET FEVER | - |
dc.subject.keywordPlus | ERYTHROMYCIN RESISTANCE | - |
dc.subject.keywordPlus | M-PROTEINS | - |
dc.subject.keywordPlus | PYOGENES | - |
dc.subject.keywordPlus | OUTBREAK | - |
dc.subject.keywordPlus | EPIDEMIOLOGY | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | PNEUMONIAE | - |
dc.subject.keywordPlus | EMERGENCE | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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