The clinical significance of a second transurethral resection for T1 high-grade bladder cancer: Results of a prospective study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shim, J.S. | - |
dc.contributor.author | Choi, H. | - |
dc.contributor.author | Noh, T.I. | - |
dc.contributor.author | Tae, J.H. | - |
dc.contributor.author | Yoon, S.G. | - |
dc.contributor.author | Kang, S.H. | - |
dc.contributor.author | Bae, J.H. | - |
dc.contributor.author | Park, H.S. | - |
dc.contributor.author | Park, J.Y. | - |
dc.date.accessioned | 2024-02-23T03:30:29Z | - |
dc.date.available | 2024-02-23T03:30:29Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 2005-6737 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/72342 | - |
dc.description.abstract | Purpose: This study was designed to estimate the value of a second transurethral resection of bladder tumor (TURBT) procedure in patients with initially diagnosed T1 high-grade bladder cancer. Materials and Methods: Between August 2009 and January 2013, a total of 29 patients with T1 high-grade bladder cancer prospectively underwent a second TURBT procedure. Evaluation included the presence of previously undetected residual tumor, changes to histopathological staging or grading, and tumor location. Recurrence-free and progression-free survival curves were generated to compare the prognosis between the groups with and without residual lesions by use of the Kaplan-Meier method. Results: Of 29 patients, 22 patients (75.9%) had residual disease after the second TURBT. Staging was as follows: no tumor, 7 (24.1%); Ta, 5 (17.2%); T1, 6 (20.7%); Tis, 6 (20.7%); Ta+Tis, 1 (3.4%); T1+Tis, 1 (3.4%); and ≥T2, 3 (10.3%). The muscle layer was included in the surgical specimen after the initial TURBT in 24 patients (82.7%). In three patients whose cancer was upstaged to pT2 after the second TURBT, the initial surgical specimen contained the muscle layer. In the group with residual lesions, the 3-year recurrence-free survival and 3-year progression-free survival rates were 50% and 66.9%, respectively, whereas these rates were 68.6% and 68.6%, respectively, in the group without residual lesions. This difference was not statistically significant. Conclusions: Initial TURBT does not seem to be enough to control T1 high-grade bladder cancer. Therefore, a routine second TURBT procedure should be recommended in patients with T1 high-grade bladder cancer to accomplish adequate tumor resection and to identify patients who may need to undergo prompt cystectomy. © The Korean Urological Association, 2015. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Korean Urological Association | - |
dc.title | The clinical significance of a second transurethral resection for T1 high-grade bladder cancer: Results of a prospective study | - |
dc.type | Article | - |
dc.identifier.doi | 10.4111/kju.2015.56.6.429 | - |
dc.identifier.bibliographicCitation | Korean Journal of Urology, v.56, no.6, pp 429 - 434 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-84930856505 | - |
dc.citation.endPage | 434 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 429 | - |
dc.citation.title | Korean Journal of Urology | - |
dc.citation.volume | 56 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Neoplasm invasiveness | - |
dc.subject.keywordAuthor | Recurrence | - |
dc.subject.keywordAuthor | Urinary bladder neoplasms | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.