Clinical Outcomes of Rhythm Control Strategies for Asymptomatic Atrial Fibrillation According to the Quality-of-Life Score: The CODE-AF (Comparison Study of Drugs for Symptom Control and Complication Prevention of Atrial Fibrillation) Registry
DC Field | Value | Language |
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dc.contributor.author | Kim, Ju Youn | - |
dc.contributor.author | Park, Hyoung-Seob | - |
dc.contributor.author | Park, Hyung Wook | - |
dc.contributor.author | Choi, Eue-Keun | - |
dc.contributor.author | Park, Jin-Kyu | - |
dc.contributor.author | Kim, Jin-Bae | - |
dc.contributor.author | Kang, Ki-Woon | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Joung, Boyoung | - |
dc.contributor.author | Park, Kyoung-Min | - |
dc.date.accessioned | 2024-02-26T03:01:02Z | - |
dc.date.available | 2024-02-26T03:01:02Z | - |
dc.date.issued | 2022-09 | - |
dc.identifier.issn | 2047-9980 | - |
dc.identifier.issn | 2047-9980 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/72430 | - |
dc.description.abstract | BACKGROUND: Atrial fibrillation (AF) is associated with an increased risk of poor cardiovascular outcomes; appropriate rhythm control can reduce the incidence of these adverse events. Therefore, catheter ablation is recommended in symptomatic patients with AF. The aims of this study were to compare AF-related outcomes according to a baseline symptom scale score and to determine the best treatment strategy for asymptomatic patients with AF. METHODS AND RESULTS: This study enrolled all patients who completed a baseline Atrial Fibrillation Effect on Quality-of-Life (AFEQT) survey in a prospective observational registry. The patients were divided into 2 groups according to AFEQT score at baseline; scores <= 80 were defined as symptomatic, whereas scores >80 represented asymptomatic patients. The primary outcome was defined as a composite of hospitalization for heart failure, ischemic stroke, or cardiac death. This study included 1515 patients (mean age: 65.7 +/- 10.5 years; 998 [65.9%] men). The survival curve showed a poorer outcome in the symptomatic group compared with the asymptomatic group (log-rank P=0.04). Rhythm control led to a significantly lower risk of a composite outcome in asymptomatic patients (hazard ratio [HR], 0.47 [95% CI, 0.27-0.84], P=0.01). Rhythm control was associated with more favorable composite outcomes in the asymptomatic group with paroxysmal AF, left atrium diameter <= 50 mm, and CHA(2)DS(2)-VASc score >= 3. CONCLUSIONS: Symptomatic patients with AF experienced more adverse outcomes compared with asymptomatic patients. In asymptomatic patients with AF, a strategy of rhythm control improved the outcomes, especially with paroxysmal AF, smaller left atrium size, or higher stroke risk. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY | - |
dc.title | Clinical Outcomes of Rhythm Control Strategies for Asymptomatic Atrial Fibrillation According to the Quality-of-Life Score: The CODE-AF (Comparison Study of Drugs for Symptom Control and Complication Prevention of Atrial Fibrillation) Registry | - |
dc.type | Article | - |
dc.identifier.doi | 10.1161/JAHA.122.025956 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN HEART ASSOCIATION, v.11, no.18 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000858504900042 | - |
dc.identifier.scopusid | 2-s2.0-85138390743 | - |
dc.citation.number | 18 | - |
dc.citation.title | JOURNAL OF THE AMERICAN HEART ASSOCIATION | - |
dc.citation.volume | 11 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | quality of life | - |
dc.subject.keywordAuthor | treatment outcome | - |
dc.subject.keywordPlus | CATHETER ABLATION | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordPlus | SIMPLE SCALE | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | PROGRESSION | - |
dc.subject.keywordPlus | VALIDATION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | SEVERITY | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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