Major determinant of the occurrence of pacing-induced cardiomyopathy in complete atrioventricular block: A multicentre, retrospective analysis over a 15-year period in South Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, J.H. | - |
dc.contributor.author | Kang, K.-W. | - |
dc.contributor.author | Chin, J.Y. | - |
dc.contributor.author | Kim, T.-S. | - |
dc.contributor.author | Park, J.-H. | - |
dc.contributor.author | Choi, Y.J. | - |
dc.date.accessioned | 2024-02-26T05:30:22Z | - |
dc.date.available | 2024-02-26T05:30:22Z | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 2044-6055 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/72461 | - |
dc.description.abstract | Objectives The predictors of pacing-induced cardiomyopathy (PICM) for complete atrioventricular block (CAVB) have not yet been defined. The aim of this study was to investigate the major determinant of the occurrence of PICM. Setting This is a multicentre, retrospective analysis of CAVB from tertiary referral centres in Daejeon, South Korea. Participants A cohort of 900 consecutive patients with an implanted pacemaker was collected from December 2001 to August 2015. Of these, a total of 130 patients with CAVB with pacing-dependent rhythm who underwent ECG and echocardiogram before and after implantation were analysed for the occurrence of PICM. Outcome measures Cox proportional hazards models evaluated the determinant of PICM by ECG, device parameters and echocardiogram over a mean of 4.5 years. Results PICM was observed in 16.1% (n=21) of all patients with CAVB (age, 64±11 years; male, 36.2%). The preimplant left ventricular (LV) ejection fraction (66%±9% vs 66%±8%) and non-apical pacing (40.4% vs 33.3%) were similar; however, the native QRS duration (124±34 ms vs 149±32 ms) and the paced QRS duration (pQRSd) (139±29 ms vs 167±28 ms) were significantly different between the two groups. The postimplant LV ejection fraction (61%±7% vs 31%±8%) was also significantly different at the end of follow-up. A pQRSd significantly correlated with PICM (HR 1.05, 95% CI 1.02 to 1.09, P=0.001). A pQRSd with a cut-off value of above 140 ms had a sensitivity of 95% while a pQRSd with a cut-off value of above 167 ms had a specificity of 90% for PICM. Conclusion In patients with CAVB with pacing-dependent rhythm, regardless of the pacing site, the pQRSd is a major determinant of the occurrence of PICM. © 2018 Article author(s). All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | BMJ Publishing Group | - |
dc.title | Major determinant of the occurrence of pacing-induced cardiomyopathy in complete atrioventricular block: A multicentre, retrospective analysis over a 15-year period in South Korea | - |
dc.type | Article | - |
dc.identifier.doi | 10.1136/bmjopen-2017-019048 | - |
dc.identifier.bibliographicCitation | BMJ Open, v.8, no.2 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85052164626 | - |
dc.citation.number | 2 | - |
dc.citation.title | BMJ Open | - |
dc.citation.volume | 8 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | cardiomyopathy | - |
dc.subject.keywordAuthor | complete AV block | - |
dc.subject.keywordAuthor | pacemaker | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.