Combination treatments employing CO2 fractional lasers with polydeoxyribonucleotide injections for chronic atrophic scar in Republic of Korea: a case report

Abstract

The use of ablative lasers for chronic atrophic scars poses a significant challenge, requiring extended downtime and leading to side effects, such as irregular dyspigmentation and post-laser erythema. This case report presents the synergistic treatment a chronic atrophic scar using a CO2 fractional laser alongside intradermal polydeoxyribonucleotide (PDRN) injections. A 25-year-old female received six sessions of a CO2 fractional laser treatment at 4-week intervals, coupled with intradermal PDRN injections. The scar exhibited remarkable improvement after treatment, and the patient was satisfied with the outcome. Combining a CO2 fractional laser with a PDRN injection can enhance wound healing, reduce downtime, and improve the clinical outcomes.