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Development of a wearable surface enhanced Raman scattering sensor chip based on silver nanowires for rapid detection of urea, lactate and pH in sweatopen access

Authors
D'Andrea, CristianoBanchelli, MartinaAmicucci, ChiaraPolykretis, PanagisMicheletti, Filippode Angelis, MarellaHwang, ByungilMatteini, Paolo
Issue Date
Apr-2024
Publisher
EDP SCIENCES S A
Keywords
Wearable sensor; SERS; Sweat; Urea; Lactate; pH; Silver nanowires
Citation
JOURNAL OF THE EUROPEAN OPTICAL SOCIETY-RAPID PUBLICATIONS, v.20, no.1
Journal Title
JOURNAL OF THE EUROPEAN OPTICAL SOCIETY-RAPID PUBLICATIONS
Volume
20
Number
1
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73552
DOI
10.1051/jeos/2024013
ISSN
1990-2573
Abstract
A wearable sweat sensor chip based on surface-enhanced Raman spectroscopy (SERS) is here presented. The plasmonic core of the chip, obtained by deposition of silver nanowires on a polytetrafluoroethylene (PTFE) porous membrane, permits the direct and label-free detection of urea and lactate at physiologic concentrations in combination with the pH measurement in the range between 5 and 9. Once integrated with commercial biocompatible and adhesive tape layers, the as produced SERS-active chip provides a low-cost, flexible and wearable sensing device for rapid and reliable human sweat analysis. The chip was finally tested on real sweat samples to estimate lactate and urea during medium-intense exertions.
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