Eosinophilia is a favorable marker for pneumonia in chronic obstructive pulmonary disease
DC Field | Value | Language |
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dc.contributor.author | Gu, Kang-Mo | - |
dc.contributor.author | Jung, Jae-Woo | - |
dc.contributor.author | Kang, Min-Jong | - |
dc.contributor.author | Kim, Deog Kyeom | - |
dc.contributor.author | Choi, Hayoung | - |
dc.contributor.author | Cho, Young-Jae | - |
dc.contributor.author | Jang, Seung Hun | - |
dc.contributor.author | Lee, Chang-Hoon | - |
dc.contributor.author | Oh, Yeon Mok | - |
dc.contributor.author | Park, Ji Sook | - |
dc.contributor.author | Kim, Jae Yeol | - |
dc.date.accessioned | 2024-05-21T09:30:19Z | - |
dc.date.available | 2024-05-21T09:30:19Z | - |
dc.date.issued | 2024-05 | - |
dc.identifier.issn | 1738-3536 | - |
dc.identifier.issn | 2005-6184 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/73873 | - |
dc.description.abstract | Patients with chronic obstructive pulmonary disease (COPD) expressing eosinophilia experience slightly fewer episodes of community-acquired pneumonia (CAP) than those without eosinophilia. However, the severity and burden of hospitalized pneumonia patients with COPD concerning eosinophilia have not been assessed. We evaluated the differences in clinical characteristics between patients with CAP and COPD with or without eosinophilia by a post-hoc analysis of a prospective, multi-center, cohort study data. Of 349 CAP patients with COPD, 45 (12.9%) had eosinophilia (blood eosinophil &#x2265; 300 cells/&#xb5;L). Patients with eosinophilia had a lower sputum culture percentile (8.1% vs. 23.4%, P < 0.05), a lower percentile of neutrophils (70.3% vs 80.2%, P<0.05), reduced C-reactive protein levels (30.6 mg/L vs 86.6 mg/L, P<0.05), and a lower pneumonia severity index score (82.5 vs. 90.0, P < 0.05) than those without eosinophilia. The duration of antibiotic treatment (8.0 days vs. 10.0 days, P < 0.05) and hospitalization (7.0 days vs. 9.0 days, P < 0.05) were shorter in eosinophilic patients. The cost of medical care per day (256.4 US$ vs. 291.0 US$, P < 0.05), cost for the medication (276.4 US$ vs. 349.9 US$, P < 0.05), and cost for examination (685.5 US$ vs 958.1 US$, P<0.05) were lower in patients with eosinophilia than those without eosinophilia. Eosinophilia serves as a favorable marker for severity of pneumonia, health-care consumption, and cost of medical care in patients with CAP and COPD. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.title | Eosinophilia is a favorable marker for pneumonia in chronic obstructive pulmonary disease | - |
dc.type | Article | - |
dc.identifier.doi | 10.4046/trd.2023.0174 | - |
dc.identifier.bibliographicCitation | Tuberculosis and respiratory diseases | - |
dc.description.isOpenAccess | Y | - |
dc.citation.title | Tuberculosis and respiratory diseases | - |
dc.type.docType | Journal Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | COPD | - |
dc.subject.keywordAuthor | cost | - |
dc.subject.keywordAuthor | eosinophilia | - |
dc.subject.keywordAuthor | pneumonia | - |
dc.subject.keywordAuthor | severity | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | esci | - |
dc.description.journalRegisteredClass | kci | - |
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