Positive Effect of Air Purifier Intervention on Baroreflex Sensitivity and Biomarkers of Oxidative Stress in Patients with Coronary Artery Disease: A Randomized Crossover Intervention Trial
DC Field | Value | Language |
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dc.contributor.author | Eom, Sang-Yong | - |
dc.contributor.author | Kim, Aryun | - |
dc.contributor.author | Lee, Ju-Hee | - |
dc.contributor.author | Kim, Sang Min | - |
dc.contributor.author | Lee, Sang-Yeub | - |
dc.contributor.author | Hwang, Kyung-Kuk | - |
dc.contributor.author | Lim, Hyun-Joung | - |
dc.contributor.author | Cho, Myeong-Chan | - |
dc.contributor.author | Kim, Yong-Dae | - |
dc.contributor.author | Bae, Jang-Whan | - |
dc.contributor.author | Kim, Jun Hyung | - |
dc.contributor.author | Lee, Dae-In | - |
dc.date.accessioned | 2024-06-10T05:00:21Z | - |
dc.date.available | 2024-06-10T05:00:21Z | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 1661-7827 | - |
dc.identifier.issn | 1660-4601 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74080 | - |
dc.description.abstract | Exposure to fine particulate matter increases the risk of cardiovascular morbidity and mortality. Few studies have tested the beneficial effect of indoor air filtration intervention in patients with cardiovascular disease. The aim of this study is to investigate the effect of air filtration on mitigating cardiovascular health in patients with coronary artery disease. This randomized, double-blind, crossover study is conducted with 38 coronary artery disease patients. The intervention consists of the following three periods: two-week active and sham air filtration interventions, with a two-week washout period. The indoor PM2.5 concentration is continuously monitored during the entire study period. We measure the blood pressure, heart rate variability, baroreflex sensitivity, autonomic function test results, and endothelial function. The two-week active air filtration intervention for two weeks reduces the average indoor concentration of PM2.5 by 33.9%. The indoor PM2.5 concentration is significantly correlated to cross-correlation baroreflex sensitivity. Active air filtration is significantly associated with a decrease in the indicator of oxidative stress represented as 8-hydroxy-2 '-deoxyguanosine. This study shows that a short-term air filtration intervention improved baroreflex sensitivity and might reduce oxidative stress in coronary artery disease patients. These findings suggest that the use of an air purifier could mitigate the recurrence of cardiovascular disease events in patients with coronary artery disease. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Positive Effect of Air Purifier Intervention on Baroreflex Sensitivity and Biomarkers of Oxidative Stress in Patients with Coronary Artery Disease: A Randomized Crossover Intervention Trial | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/ijerph19127078 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, v.19, no.12 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000817720600001 | - |
dc.identifier.scopusid | 2-s2.0-85131675825 | - |
dc.citation.number | 12 | - |
dc.citation.title | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | - |
dc.citation.volume | 19 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | particulate matter | - |
dc.subject.keywordAuthor | air purifier | - |
dc.subject.keywordAuthor | baroreflex sensitivity | - |
dc.subject.keywordAuthor | oxidative stress | - |
dc.subject.keywordAuthor | coronary artery disease | - |
dc.subject.keywordPlus | FINE PARTICULATE MATTER | - |
dc.subject.keywordPlus | URINARY 8-HYDROXY-2'-DEOXYGUANOSINE | - |
dc.subject.keywordPlus | MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | INDOOR PARTICLES | - |
dc.subject.keywordPlus | FILTRATION | - |
dc.subject.keywordPlus | POLLUTION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | HEALTH | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | EXPOSURE | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalResearchArea | Public, Environmental & Occupational Health | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.relation.journalWebOfScienceCategory | Public, Environmental & Occupational Health | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
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