Differences in factors associated with insomnia symptoms between patients with epilepsy with and without depressive symptoms
DC Field | Value | Language |
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dc.contributor.author | Lee, Sang-Ahm | - |
dc.contributor.author | Choi, Eun Ju | - |
dc.contributor.author | Kim, Hyun-Woo | - |
dc.contributor.author | Jeon, Ji-Ye | - |
dc.contributor.author | Han, Su-Hyun | - |
dc.contributor.author | Lee, Gha-Hyun | - |
dc.contributor.author | Ryu, Han Uk | - |
dc.contributor.author | Kim, Boyoung | - |
dc.contributor.author | Kim, Tae-Young | - |
dc.date.accessioned | 2024-06-17T02:30:28Z | - |
dc.date.available | 2024-06-17T02:30:28Z | - |
dc.date.issued | 2024-07 | - |
dc.identifier.issn | 1525-5050 | - |
dc.identifier.issn | 1525-5069 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74224 | - |
dc.description.abstract | Objective: To determine if insomnia-related factors differ depending on the presence of depression in patients with epilepsy. Methods: This cross-sectional multicenter study collected data on depressive symptoms, insomnia symptoms, and excessive daytime sleepiness, which were defined as a Patient Health Questionnaire-9 (PHQ-9) score of ≥ 10, an Insomnia Severity Index (ISI) score of ≥ 15, and an Epworth Sleepiness Scale (ESS) of ≥ 11, respectively. Further, uncontrolled seizures were defined as one or more seizures per month during antiseizure medications treatment. A stepwise logistic regression analysis was conducted, with a logistic regression with interaction terms performed to identify differences in insomnia-related factors depending on depressive symptoms. Results: Of 282 adults with epilepsy (men, 58 %; mean age, 40.4 ± 13.9 years), a PHQ-9 score ≥ 10, an ISI score ≥ 15, an ESS score ≥ 11 were noted in 23.4 % (n = 66), 20.2 % (n = 57), and 12.8 % (n = 36), respectively. More patients with depressive symptoms had an ISI score ≥ 15 (56.1 % vs. 9.3 %; p < 0.001) than those without. In multiple logistic regression, uncontrolled seizures (odds ratio [OR], 4.896; p < 0.01), daytime sleepiness (OR, 5.369; p < 0.05), and a history of psychiatric disorders (OR, 3.971; p < 0.05) were identified as significant factors that were more likely to be associated with an ISI score ≥ 15; however, this was only true in patients without depressive symptoms. In contrast, use of perampanel (OR, 0.282; p < 0.05) was less likely associated, while female sex (OR, 3.178; p < 0.05) was more likely associated with an ISI score ≥ 15 only in patients with depressive symptoms. Conclusions: Insomnia-related factors in patients with epilepsy may differ between patients with and without depression. Our findings of different insomnia-related factors based on the presence of depression may facilitate the management of patients with epilepsy. © 2024 Elsevier Inc. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Academic Press Inc. | - |
dc.title | Differences in factors associated with insomnia symptoms between patients with epilepsy with and without depressive symptoms | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.yebeh.2024.109781 | - |
dc.identifier.bibliographicCitation | Epilepsy and Behavior, v.156 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 001246457500001 | - |
dc.identifier.scopusid | 2-s2.0-85193574860 | - |
dc.citation.title | Epilepsy and Behavior | - |
dc.citation.volume | 156 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Daytime sleepiness | - |
dc.subject.keywordAuthor | Depression | - |
dc.subject.keywordAuthor | Epilepsy | - |
dc.subject.keywordAuthor | Insomnia | - |
dc.subject.keywordAuthor | Perampanel | - |
dc.subject.keywordAuthor | Sleep disturbance | - |
dc.subject.keywordPlus | SUBJECTIVE SLEEP DISTURBANCE | - |
dc.subject.keywordPlus | ADJUNCTIVE PERAMPANEL | - |
dc.subject.keywordPlus | DAYTIME SLEEPINESS | - |
dc.subject.keywordPlus | QUALITY | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | VALIDATION | - |
dc.subject.keywordPlus | SEVERITY | - |
dc.subject.keywordPlus | ARCHITECTURE | - |
dc.subject.keywordPlus | LAMOTRIGINE | - |
dc.subject.keywordPlus | DISORDERS | - |
dc.relation.journalResearchArea | Behavioral Sciences | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Behavioral Sciences | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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