Evaluation of pre-induction dynamic arterial elastance as an adjustable predictor of post-induction hypotension: A prospective observational studyopen access
- Authors
- Oh, E.J.; Min, J.J.; Kwon, E.; Choi, E.A.; Lee, J.-H.
- Issue Date
- Aug-2023
- Publisher
- Elsevier Inc.
- Keywords
- Arterial load; Dynamic arterial elastance; General anesthesia; Post-induction hypotension; Pulse pressure variation (PPV); Stroke volume variation (SVV)
- Citation
- Journal of Clinical Anesthesia, v.87
- Journal Title
- Journal of Clinical Anesthesia
- Volume
- 87
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74306
- DOI
- 10.1016/j.jclinane.2023.111092
- ISSN
- 0952-8180
1873-4529
- Abstract
- Study objective: Dynamic arterial elastance (Eadyn) has been suggested as a functional measure of arterial load. We aimed to evaluate whether pre-induction Eadyn can predict post-induction hypotension. Design: Prospective observational study. Patients: Adult patients undergoing general anesthesia with invasive and non-invasive arterial pressure monitoring systems. Measurements: We collected invasive and non-invasive Eadyns (n = 38 in each), respectively. In both invasive and non-invasive Eadyns, pre-induction Eadyns were obtained during one-minute tidal and deep breathing in each patient before anesthetic induction. Post-induction hypotension was defined as a decrease of >30% in mean blood pressure from the baseline value or any absolute mean blood pressure value of <65 mmHg for 10 min after anesthetic induction. The predictabilities of Eadyns for the development of post-induction hypotension were tested using receiver-operating characteristic curve analysis. Main results: Invasive Eadyn during deep breathing showed significant predictability with an area under the curve (AUC) of 0.78 (95% Confidence interval [CI], 0.61–0.90, P = 0.001). But non-invasive Eadyn during tidal breathing (AUC = 0.66, 95% CI, 0.49–0.81, P = 0.096) and deep breathing (AUC = 0.53, 95% CI, 0.36–0.70, P = 0.75), and invasive Eadyn during tidal breathing (AUC = 0.66, 95% CI, 0.41–0.74, P = 0.095) failed to predict post-induction hypotension. Conclusion: In our study, invasive pre-induction Eadyn during deep breathing -could predict post-induction hypotension. Despite its invasiveness, future studies will be needed to evaluate the usefulness of Eadyn as a predictor of post-induction hypotension because it is an adjustable parameter. © 2023 The Authors
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