Forced-air prewarming prevents hypothermia during living donor liver transplantation: a randomized controlled trial
DC Field | Value | Language |
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dc.contributor.author | Oh, E.J. | - |
dc.contributor.author | Han, S. | - |
dc.contributor.author | Lee, S. | - |
dc.contributor.author | Choi, E.A. | - |
dc.contributor.author | Ko, J.S. | - |
dc.contributor.author | Gwak, M.S. | - |
dc.contributor.author | Kim, G.S. | - |
dc.date.accessioned | 2024-06-20T01:30:57Z | - |
dc.date.available | 2024-06-20T01:30:57Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74307 | - |
dc.description.abstract | Despite various intraoperative thermal strategies, core heat loss is considerable during liver transplantation and hypothermia is common. We tested whether forced-air prewarming prevents hypothermia during liver transplantation. Adult patients undergoing living donor liver transplantation were randomly assigned to non-prewarming group (n = 20) or prewarming group (n = 20). Patients in prewarming group underwent 30-min forced-air warming before anesthetic induction. During surgery, core temperature was measured in the pulmonary artery. The primary outcome was intraoperative hypothermia (< 36.0 °C). The secondary outcomes included plasma lactate concentration. Intraoperative hypothermia risk was significantly lower in prewarming group than in non-prewarming group (60.0% vs. 95.0%, P = 0.020). The difference in hypothermia incidence between groups was greater in the post-induction phase (20.0% vs. 85.0%, P < 0.001) than in the anhepatic or post-reperfusion phase, suggesting that prewarming mainly acts on preventing post-induction core-to-peripheral heat redistribution. Hypothermia duration was significantly shorter in prewarming group (60 [0-221] min vs. 383 [108-426] min, P = 0.001). Lactate concentration decreased during 3 h after graft reperfusion in prewarming group, whereas it continuously increased in non-prewarming group (- 0.19 [- 0.48 to 0.13] mmol/L vs. 1.17 [3.31-0.77] mmol/L, P = 0.034). In conclusion, forced-air prewarming decreases the incidence and duration of intraoperative hypothermia with potential clinical benefit while mainly acting by preventing the core-to-peripheral heat redistribution.Clinical trial registration: Registered at the Clinical Research Information Service ( https://cris.nih.go.kr , [KCT0003230]) on 01/10/2018. © 2023. The Author(s). | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NLM (Medline) | - |
dc.title | Forced-air prewarming prevents hypothermia during living donor liver transplantation: a randomized controlled trial | - |
dc.type | Article | - |
dc.identifier.doi | 10.1038/s41598-022-23930-2 | - |
dc.identifier.bibliographicCitation | Scientific reports, v.13, no.1 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 001049981800004 | - |
dc.identifier.scopusid | 2-s2.0-85151901839 | - |
dc.citation.number | 1 | - |
dc.citation.title | Scientific reports | - |
dc.citation.volume | 13 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordPlus | MILD PERIOPERATIVE HYPOTHERMIA | - |
dc.subject.keywordPlus | BODY CORE TEMPERATURE | - |
dc.subject.keywordPlus | BLOOD-COAGULATION | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | COMPLICATIONS | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | NORMOTHERMIA | - |
dc.subject.keywordPlus | DURATION | - |
dc.subject.keywordPlus | TIME | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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