Randomized Clinical Trial of Moderate Versus Deep Neuromuscular Block for Low-Pressure Pneumoperitoneum During Laparoscopic Cholecystectomy
DC Field | Value | Language |
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dc.contributor.author | Koo, Bon-Wook | - |
dc.contributor.author | Oh, Ah-Young | - |
dc.contributor.author | Seo, Kwang-Suk | - |
dc.contributor.author | Han, Ji-Won | - |
dc.contributor.author | Han, Ho-Seong | - |
dc.contributor.author | Yoon, Yoo-Seok | - |
dc.date.accessioned | 2024-06-28T02:00:27Z | - |
dc.date.available | 2024-06-28T02:00:27Z | - |
dc.date.issued | 2016-12 | - |
dc.identifier.issn | 0364-2313 | - |
dc.identifier.issn | 1432-2323 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74410 | - |
dc.description.abstract | The beneficial effects of deep blockade are not fully known. In this study, we evaluated the effect of deep neuromuscular blockade on surgical conditions during laparoscopic cholecystectomy under low-pressure pneumoperitoneum. Patients undergoing elective laparoscopic cholecystectomy were randomized to either the moderate group (train-of-four count of 1 or 2) or deep group (posttetanic count of 1 or 2). Neuromuscular blockade was induced and maintained with rocuronium; it was reversed with sugammadex in the deep group and with neostigmine in the moderate group. At the beginning of surgery, the intra-abdominal pressure was set at 8 mmHg. The surgeon rated the surgical condition on a 4-point scale (1 = excellent, 2 = good, 3 = acceptable, 4 = poor) and was allowed to increase the pressure to 12 mmHg if it was determined that the surgical conditions were inadequate for the operation. A total of 64 patients completed the study. The rate of increasing intra-abdominal pressure to maintain optimal surgical conditions was 34.4 % in the moderate group and 12.5 % in the deep group (P = 0.039). The proportion of patients with a surgical condition score of 1 or 2 (excellent or good) was 34.4 % in the moderate group and 68.8 % in the deep group (P = 0.006). The maintenance of intraoperative deep neuromuscular blockade was associated with a lower rate of conversion to standard pressure and higher surgeon satisfaction with the surgical conditions than was moderate blockade in patients undergoing low-pressure pneumoperitoneum laparoscopic cholecystectomy. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Randomized Clinical Trial of Moderate Versus Deep Neuromuscular Block for Low-Pressure Pneumoperitoneum During Laparoscopic Cholecystectomy | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s00268-016-3633-8 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF SURGERY, v.40, no.12, pp 2898 - 2903 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000387709300010 | - |
dc.identifier.scopusid | 2-s2.0-84978132206 | - |
dc.citation.endPage | 2903 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 2898 | - |
dc.citation.title | WORLD JOURNAL OF SURGERY | - |
dc.citation.volume | 40 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | SURGICAL CONDITIONS | - |
dc.subject.keywordPlus | STANDARD-PRESSURE | - |
dc.subject.keywordPlus | SUGAMMADEX | - |
dc.subject.keywordPlus | NEOSTIGMINE | - |
dc.subject.keywordPlus | REVERSAL | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | MUSCLES | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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