Postoperative residual neuromuscular blockade after reversal based on a qualitative peripheral nerve stimulator response A randomised controlled trial
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Yea-Ji | - |
dc.contributor.author | Oh, Ah-Young | - |
dc.contributor.author | Koo, Bon-Woo | - |
dc.contributor.author | Han, Ji-Won | - |
dc.contributor.author | Park, Jae-Hee | - |
dc.contributor.author | Hong, Jung-Pyo | - |
dc.contributor.author | Seo, Kwang-Suk | - |
dc.date.accessioned | 2024-06-28T02:30:29Z | - |
dc.date.available | 2024-06-28T02:30:29Z | - |
dc.date.issued | 2020-03 | - |
dc.identifier.issn | 0265-0215 | - |
dc.identifier.issn | 1365-2346 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74420 | - |
dc.description.abstract | BACKGROUND Incomplete recovery of neuromuscular blockade is a common postoperative adverse event in the postanaesthesia care unit. OBJECTIVE We examined and compared the incidence of residual neuromuscular blockade when the recommended dose of neostigmine or sugammadex was administered according to a qualitative nerve stimulator response. DESIGN A randomised controlled trial. SETTING A tertiary care hospital in South Korea from September 2017 to November 2017. PATIENTS Eighty patients aged between 18 and 69 years were included in this study. All were patients scheduled to undergo elective laparoscopic cholecystectomy and who had an American Society of Anaesthesiologists physical status of one or two were eligible. INTERVENTIONS Patients were allocated randomly to receive neostigmine or sugammadex at the end of surgery. The doses of the reversal agents were based on the response to peripheral nerve stimulation, which was discontinued after administration of the reversal agent. MAIN OUTCOME MEASURES The primary outcome was the incidence of postoperative residual neuromuscular blockade. The secondary outcomes were the incidences of symptoms or signs of residual neuromuscular blockade such as hypoxaemia, inability to maintain head-lift for 5 s and diplopia. RESULTS The incidence of residual neuromuscular blockade on arrival in the recovery room was 44.4% in the neostigmine group and 0% in the sugammadex group (P < 0.0001, relative risk = 1.80, 95% confidence interval 1.36 to 2.41). The incidences of adverse events in the recovery room were low and comparable between the groups. CONCLUSION The incidence of residual neuromuscular blockade on arrival in the recovery room was significantly higher in the neostigmine group than that in the sugammadex group. However, the incidence of adverse events was similar in the neostigmine and sugammadex groups. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.title | Postoperative residual neuromuscular blockade after reversal based on a qualitative peripheral nerve stimulator response A randomised controlled trial | - |
dc.type | Article | - |
dc.identifier.doi | 10.1097/EJA.0000000000001157 | - |
dc.identifier.bibliographicCitation | EUROPEAN JOURNAL OF ANAESTHESIOLOGY, v.37, no.3, pp 196 - 202 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000524571800006 | - |
dc.identifier.scopusid | 2-s2.0-85079101050 | - |
dc.citation.endPage | 202 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 196 | - |
dc.citation.title | EUROPEAN JOURNAL OF ANAESTHESIOLOGY | - |
dc.citation.volume | 37 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | NEOSTIGMINE | - |
dc.subject.keywordPlus | TRAIN-OF-4 | - |
dc.subject.keywordPlus | ROCURONIUM | - |
dc.subject.keywordPlus | ANESTHESIA | - |
dc.subject.keywordPlus | PARALYSIS | - |
dc.subject.keywordPlus | RECOVERY | - |
dc.relation.journalResearchArea | Anesthesiology | - |
dc.relation.journalWebOfScienceCategory | Anesthesiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.