Nutritional safety of oncometabolic surgery for early gastric cancer patients: a prospective single-arm pilot study using a historical control group for comparison
DC Field | Value | Language |
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dc.contributor.author | Park, Young Suk | - |
dc.contributor.author | Park, Do Joong | - |
dc.contributor.author | Kim, Ki Hyun | - |
dc.contributor.author | Park, Dong Jin | - |
dc.contributor.author | Lee, Yoontaek | - |
dc.contributor.author | Park, Ki Bum | - |
dc.contributor.author | Min, Sa-Hong | - |
dc.contributor.author | Ahn, Sang-Hoon | - |
dc.contributor.author | Kim, Hyung-Ho | - |
dc.date.accessioned | 2024-07-18T00:30:21Z | - |
dc.date.available | 2024-07-18T00:30:21Z | - |
dc.date.issued | 2020-01 | - |
dc.identifier.issn | 0930-2794 | - |
dc.identifier.issn | 1432-2218 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/74885 | - |
dc.description.abstract | Background Oncometabolic surgery (OS) is a modification of the Roux-en Y reconstruction method, in which the lengths of the biliopancreatic and Roux limbs are longer than that with conventional surgery (CS). Although OS is performed to improve postoperative glycemic control in gastric cancer patients with type 2 diabetes mellitus (T2DM), its postoperative nutritional safety has not been clarified. This prospective pilot study evaluated the safety and feasibility of OS in early gastric cancer patients. Methods This study evaluated 20 patients with clinical T1N0 stage and preoperative body mass index (BMI) >= 32.5 kg/m(2), or >= 27.5 kg/m(2) with comorbidities, who underwent OS. Primary outcomes were cumulative incidences of anemia and deficiencies in iron and vitamin B12 after 1 year. The outcomes were compared to those of a matched historical control group. Results The cumulative incidences of anemia (15.0% vs. 10.0%, P = 0.99), iron deficiency (15.0% vs. 10.0%, P = 0.99), and vitamin B12 deficiency (10.0% vs. 0%, P = 0.47) did not differ significantly in the OS and CS groups. However, median vitamin B12 concentration tended to be lower (395.8 vs. 493.7 pg/mL, P = 0.06) and reductions in vitamin B12 concentration tended to be greater (174.7 vs. 123.0 pg/mL, P = 0.07) in the OS group. BMI loss was similar in the two groups (2.9 vs. 2.8 kg/m(2), P = 0.80). Remission rates of hypertension (68.8% vs. 41.2%, P = 0.22) and T2DM (77.8% vs. 50.0%, P = 0.58) were higher in the OS group. Conclusion Nutritional parameters did not differ significantly in the OS and CS groups. Vitamin B12 levels should be carefully monitored after OS. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Nutritional safety of oncometabolic surgery for early gastric cancer patients: a prospective single-arm pilot study using a historical control group for comparison | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s00464-019-06763-5 | - |
dc.identifier.bibliographicCitation | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, v.34, no.1, pp 275 - 283 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000527100200023 | - |
dc.identifier.scopusid | 2-s2.0-85064266612 | - |
dc.citation.endPage | 283 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 275 | - |
dc.citation.title | SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | - |
dc.citation.volume | 34 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Stomach neoplasm | - |
dc.subject.keywordAuthor | Nutritional status | - |
dc.subject.keywordAuthor | Obesity | - |
dc.subject.keywordAuthor | Metabolic syndrome | - |
dc.subject.keywordAuthor | Reconstructive surgical procedures | - |
dc.subject.keywordPlus | INTENSIVE MEDICAL THERAPY | - |
dc.subject.keywordPlus | TYPE-2 DIABETES-MELLITUS | - |
dc.subject.keywordPlus | EN-Y RECONSTRUCTION | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | BARIATRIC SURGERY | - |
dc.subject.keywordPlus | BYPASS ENTERITIS | - |
dc.subject.keywordPlus | GASTRECTOMY | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | TRIAL | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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