Evaluation of the impact of glycemic status on the progression of coronary artery calcification in asymptomatic individuals
DC Field | Value | Language |
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dc.contributor.author | Won, Ki-Bum | - |
dc.contributor.author | Han, Donghee | - |
dc.contributor.author | Lee, Ji Hyun | - |
dc.contributor.author | Lee, Sang-Eun | - |
dc.contributor.author | Sung, Ji Min | - |
dc.contributor.author | Choi, Su-Yeon | - |
dc.contributor.author | Chun, Eun Ju | - |
dc.contributor.author | Park, Sung Hak | - |
dc.contributor.author | Han, Hae-Won | - |
dc.contributor.author | Sung, Jidong | - |
dc.contributor.author | Jung, Hae Ok | - |
dc.contributor.author | Chang, Hyuk-Jae | - |
dc.date.accessioned | 2024-07-25T04:31:49Z | - |
dc.date.available | 2024-07-25T04:31:49Z | - |
dc.date.issued | 2018-01 | - |
dc.identifier.issn | 1475-2840 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/75134 | - |
dc.description.abstract | Background: Data on the influence of glycemic status on the progression of coronary calcification, an important marker for future adverse cardiovascular events, are limited. Methods: Data from the Korea Initiatives on Coronary Artery Calcification (KOICA) registry on 12,441 asymptomatic Korean adults (52 +/- 9 years, 84.2% males) without previous history of coronary artery disease and stroke, who underwent serial coronary artery calcification (CAC) screening examinations, were included in this study. The median inter-scan period was 3.0 (2.0-4.8) years. All participants were categorized into three groups based on their glycemic status: normal (n = 6578), pre-diabetes (n = 4146), and diabetes (n = 1717). CAC progression was defined as a difference >= 2.5 between the square roots (root) of the baseline and follow-up CAC scores. Results: The incidence of CAC progression was significantly different between the three groups (normal, 26.3%; pre-diabetes, 30.9%; and diabetes, 46.9%; p < 0.001). In the univariate logistic analysis, the risk of CAC progression was higher in the pre-diabetes (odds ratio [OR] 1.253; 95% confidential interval [CI] 1.150-1.366) and diabetes (OR 2.471; 95% CI 2.215-2.758) groups than in the normal group (p < 0.001, both). In the multivariate logistic analysis, the risk of CAC progression was not significantly different between the normal and pre-diabetes groups but was significantly higher in the diabetes group than in the normal group. Conclusions: In asymptomatic subjects, diabetes had an incremental impact on CAC progression; however, prediabetes did not increase the risk of CAC progression after adjusting for confounding factors. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | BIOMED CENTRAL LTD | - |
dc.title | Evaluation of the impact of glycemic status on the progression of coronary artery calcification in asymptomatic individuals | - |
dc.type | Article | - |
dc.identifier.doi | 10.1186/s12933-017-0653-0 | - |
dc.identifier.bibliographicCitation | CARDIOVASCULAR DIABETOLOGY, v.17 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000419532400004 | - |
dc.identifier.scopusid | 2-s2.0-85042504688 | - |
dc.citation.title | CARDIOVASCULAR DIABETOLOGY | - |
dc.citation.volume | 17 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Pre-diabetes | - |
dc.subject.keywordAuthor | Diabetes | - |
dc.subject.keywordAuthor | Coronary artery calcification | - |
dc.subject.keywordPlus | BEAM COMPUTED-TOMOGRAPHY | - |
dc.subject.keywordPlus | IMPAIRED FASTING GLUCOSE | - |
dc.subject.keywordPlus | HEART-DISEASE | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | DIABETES-MELLITUS | - |
dc.subject.keywordPlus | HEMOGLOBIN A(1C) | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | CALCIUM | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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