ECMO is associated with decreased hospital mortality in COVID-19 ARDS
DC Field | Value | Language |
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dc.contributor.author | Kim, Won-Young | - |
dc.contributor.author | Jung, Sun-Young | - |
dc.contributor.author | Kim, Jeong-Yeon | - |
dc.contributor.author | Chae, Ganghee | - |
dc.contributor.author | Kim, Junghyun | - |
dc.contributor.author | Joh, Joon-Sung | - |
dc.contributor.author | Park, Tae Yun | - |
dc.contributor.author | Baek, Ae-Rin | - |
dc.contributor.author | Jegal, Yangjin | - |
dc.contributor.author | Chung, Chi Ryang | - |
dc.contributor.author | Lee, Jinwoo | - |
dc.contributor.author | Cho, Young-Jae | - |
dc.contributor.author | Park, Joo Hun | - |
dc.contributor.author | Hwang, Jung Hwa | - |
dc.contributor.author | Song, Jin Woo | - |
dc.date.accessioned | 2024-07-25T11:30:22Z | - |
dc.date.available | 2024-07-25T11:30:22Z | - |
dc.date.issued | 2024-06 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/75158 | - |
dc.description.abstract | This study determined whether compared to conventional mechanical ventilation (MV), extracorporeal membrane oxygenation (ECMO) is associated with decreased hospital mortality or fibrotic changes in patients with COVID-19 acute respiratory distress syndrome. A cohort of 72 patients treated with ECMO and 390 with conventional MV were analyzed (February 2020-December 2021). A target trial was emulated comparing the treatment strategies of initiating ECMO vs no ECMO within 7&#xa0;days of MV in patients with a PaO2/FiO2&#x2009;<&#x2009;80 or a PaCO2&#x2009;&#x2265;&#x2009;60&#xa0;mmHg. A total of 222 patients met the eligibility criteria for the emulated trial, among whom 42 initiated ECMO. ECMO was associated with a lower risk of hospital mortality (hazard ratio [HR], 0.56; 95% confidence interval [CI] 0.36-0.96). The risk was lower in patients who were younger (age&#x2009;<&#x2009;70&#xa0;years), had less comorbidities (Charlson comorbidity index&#x2009;<&#x2009;2), underwent prone positioning before ECMO, and had driving pressures&#x2009;&#x2265;&#x2009;15 cmH2O at inclusion. Furthermore, ECMO was associated with a lower risk of fibrotic changes (HR, 0.30; 95% CI 0.11-0.70). However, the finding was limited due to relatively small number of patients and differences in observability between the ECMO and conventional MV groups. © 2024. The Author(s). | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | ECMO is associated with decreased hospital mortality in COVID-19 ARDS | - |
dc.type | Article | - |
dc.identifier.doi | 10.1038/s41598-024-64949-x | - |
dc.identifier.bibliographicCitation | Scientific reports, v.14, no.1 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 001258394400076 | - |
dc.identifier.scopusid | 2-s2.0-85197155078 | - |
dc.citation.number | 1 | - |
dc.citation.title | Scientific reports | - |
dc.citation.volume | 14 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordPlus | EXTRACORPOREAL MEMBRANE-OXYGENATION | - |
dc.subject.keywordPlus | RESPIRATORY-DISTRESS-SYNDROME | - |
dc.subject.keywordPlus | LONG-TERM OUTCOMES | - |
dc.subject.keywordPlus | EVOLVING OUTCOMES | - |
dc.subject.keywordPlus | DRIVING PRESSURE | - |
dc.subject.keywordPlus | SUPPORT | - |
dc.subject.keywordPlus | STANDARDIZATION | - |
dc.subject.keywordPlus | COHORT | - |
dc.subject.keywordPlus | SCORE | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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