Cytotoxic effects of strawberry, Korean raspberry, and mulberry extracts on human ovarian cancer A2780 cells
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, D. | - |
dc.contributor.author | Kang, K.S. | - |
dc.contributor.author | Lee, S. | - |
dc.contributor.author | Cho, E.J. | - |
dc.contributor.author | Kim, H.Y. | - |
dc.date.available | 2019-03-08T15:57:00Z | - |
dc.date.issued | 2016-12 | - |
dc.identifier.issn | 2287-1098 | - |
dc.identifier.issn | 2287-8602 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/8640 | - |
dc.description.abstract | Reactive oxygen species are tumorigenic by their ability to increase cell proliferation, survival, and cellular migration. The purpose of the present study was to compare the antioxidant activity and cytotoxic effects of 3 berry extracts (strawberry, Korean raspberry, and mulberry) in A2780 human ovarian carcinoma cells. Except for raspberry, the ethyl acetate or methylene chloride fractions of berries containing phenolic compounds exerted dose dependent free radical scavenging activities. In the raspberry fractions, the hexane fraction also exhibited potent antioxidant activity. The cytotoxic effects of berries extracts in A2780 human ovarian carcinoma cells were measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Surprisingly, co-treatment with n-butanol (BuOH) fractions of berries showed stronger cytotoxic effects compared to the other fractions. These findings suggest that potent anticancer molecules are found in the BuOH fractions of berries that have stronger cytotoxic activity than antioxidants. Copyright © 2016 by The Korean Society of Food Science and Nutrition. All rights Reserved. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Korean Society of Food Science and Nutrition | - |
dc.title | Cytotoxic effects of strawberry, Korean raspberry, and mulberry extracts on human ovarian cancer A2780 cells | - |
dc.type | Article | - |
dc.identifier.doi | 10.3746/pnf.2016.21.4.384 | - |
dc.identifier.bibliographicCitation | Preventive Nutrition and Food Science, v.21, no.4, pp 384 - 388 | - |
dc.identifier.kciid | ART002182840 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.scopusid | 2-s2.0-85011591449 | - |
dc.citation.endPage | 388 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 384 | - |
dc.citation.title | Preventive Nutrition and Food Science | - |
dc.citation.volume | 21 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Antioxidant | - |
dc.subject.keywordAuthor | Berry | - |
dc.subject.keywordAuthor | Cytotoxic effect | - |
dc.subject.keywordAuthor | Ovarian cancer | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.