PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine
DC Field | Value | Language |
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dc.contributor.author | Lee, Ji-Hyun | - |
dc.contributor.author | Park, Kyoung Mii | - |
dc.contributor.author | Han, Dong-Jin | - |
dc.contributor.author | Bang, Nam Young | - |
dc.contributor.author | Kim, Do-Hee | - |
dc.contributor.author | Na, Hyeongjin | - |
dc.contributor.author | Lim, Semi | - |
dc.contributor.author | Kim, Tae Bum | - |
dc.contributor.author | Kim, Dae Gyu | - |
dc.contributor.author | Kim, Hyun-Jung | - |
dc.contributor.author | Chung, Yeonseok | - |
dc.contributor.author | Sung, Sang Hyun | - |
dc.contributor.author | Surh, Young-Joon | - |
dc.contributor.author | Kim, Sunghoon | - |
dc.contributor.author | Han, Byung Woo | - |
dc.date.available | 2019-03-08T16:36:48Z | - |
dc.date.issued | 2015-11-10 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/8913 | - |
dc.description.abstract | Despite the growing attention given to Traditional Medicine (TM) worldwide, there is no wellknown, publicly available, integrated bio-pharmacological Traditional Korean Medicine (TKM) database for researchers in drug discovery. In this study, we have constructed PharmDB-K, which offers comprehensive information relating to TKM-associated drugs (compound), disease indication, and protein relationships. To explore the underlying molecular interaction of TKM, we integrated fourteen different databases, six Pharmacopoeias, and literature, and established a massive bio-pharmacological network for TKM and experimentally validated some cases predicted from the PharmDB-K analyses. Currently, PharmDB-K contains information about 262 TKMs, 7,815 drugs, 3,721 diseases, 32,373 proteins, and 1,887 side effects. One of the unique sets of information in PharmDB-K includes 400 indicator compounds used for standardization of herbal medicine. Furthermore, we are operating PharmDB-K via phExplorer (a network visualization software) and BioMart (a data federation framework) for convenient search and analysis of the TKM network. Database URL: http://pharmdb-k.org, http://biomart.i-pharm.org. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.title | PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine | - |
dc.type | Article | - |
dc.identifier.doi | 10.1371/journal.pone.0142624 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.10, no.11 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000364430700143 | - |
dc.identifier.scopusid | 2-s2.0-84953256520 | - |
dc.citation.number | 11 | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 10 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | NF-KAPPA-B | - |
dc.subject.keywordPlus | COX-2 EXPRESSION | - |
dc.subject.keywordPlus | CHINESE MEDICINE | - |
dc.subject.keywordPlus | INFORMATION | - |
dc.subject.keywordPlus | UPDATE | - |
dc.subject.keywordPlus | SCHIZANDRIN | - |
dc.subject.keywordPlus | MECHANISM | - |
dc.subject.keywordPlus | RESOURCE | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | CELLS | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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