Recent Advances in Inorganic Nanoparticle-Based NIR Luminescence Imaging: Semiconductor Nanoparticles and Lanthanide Nanoparticles
- Authors
- Kim, Dokyoon; Lee, Nohyun; Park, Yong Il; Hyeon, Taeghwan
- Issue Date
- Jan-2017
- Publisher
- American Chemical Society
- Citation
- Bioconjugate Chemistry, v.28, no.1, pp.115 - 123
- Indexed
- SCIE
SCOPUS
- Journal Title
- Bioconjugate Chemistry
- Volume
- 28
- Number
- 1
- Start Page
- 115
- End Page
- 123
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/10593
- DOI
- 10.1021/acs.bioconjchem.6b00654
- ISSN
- 1043-1802
- Abstract
- Several types of nanoparticle-based imaging probes have been developed to replace conventional luminescent probes. For luminescence imaging, near-infrared (NIR) probes are useful in that they allow deep tissue penetration and high spatial resolution as a result of reduced light absorption/scattering and negligible autofluorescence in biological media. They rely on either an anti-Stokes or a Stokes shift process to generate luminescence. For example, transition metal-doped semiconductor nanoparticles and lanthanide-doped inorganic nanoparticles have been demonstrated as anti-Stokes shift-based agents that absorb NIR light through two- or three-photon absorption process and upconversion process, respectively. On the other hand, quantum dots (QDs) and lanthanide-doped nanoparticles that emit in NIR-II range (similar to 1000 to similar to 1350 nm) were suggested as promising Stokes shift-based imaging agents. In this topical review, we summarize and discuss the recent progress in the development of inorganic nanoparticle-based luminescence imaging probes working in NIR range.
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