A Chromo-Fluorogenic Naphthoquinolinedione-Based Probe for Dual Detection of Cu2+ and Its Use for Various Water Samples
DC Field | Value | Language |
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dc.contributor.author | Kumar, Ashwani | - |
dc.contributor.author | Kumar, Subodh | - |
dc.contributor.author | Chae, Pil Seok | - |
dc.date.accessioned | 2022-07-18T01:19:27Z | - |
dc.date.available | 2022-07-18T01:19:27Z | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.issn | 1420-3049 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/107961 | - |
dc.description.abstract | The presence of an abnormal amount of Cu2+ in the human body causes various health issues. In the current study, we synthesized a new naphthoquinolinedione-based probe (probe 1) to monitor Cu2+ in different water systems, such as tap water, lakes, and drain water. Two triazole units were introduced into the probe via a click reaction to increase the binding affinity to a metal ion. In day-light, probe 1 dissolved in a mixed solvent system (HEPES: EtOH = 1:4) showed a vivid color change from light greenish-yellow to pink in the presence of only Cu2+ among various metal ions. In addition, the green luminescence and fluorescence emission of the probe were effectively bleached out immediately after Cu2+ addition. The limit of detection (LOD) of the probe was 0.5 mu M when a ratio-metric method was used for metal ion detection. The fluorescence titration data of the probe with Cu2+ showed a calculated LOD of 41.5 pM. Hence, probe 1 possesses the following dual response toward Cu2+ detection: color change and fluorescence quenching. Probe 1 was also useful for detecting Cu2+ spiked in tap/lake water as well as the cytoplasm of live HeLa cells. The current system was investigated using ultraviolet-visible and fluorescence spectroscopy as well as density functional theory calculations (DFT). | - |
dc.format.extent | 15 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | - |
dc.title | A Chromo-Fluorogenic Naphthoquinolinedione-Based Probe for Dual Detection of Cu2+ and Its Use for Various Water Samples | - |
dc.type | Article | - |
dc.publisher.location | 스위스 | - |
dc.identifier.doi | 10.3390/molecules27030785 | - |
dc.identifier.scopusid | 2-s2.0-85123526387 | - |
dc.identifier.wosid | 000755961400001 | - |
dc.identifier.bibliographicCitation | Molecules, v.27, no.3, pp 1 - 15 | - |
dc.citation.title | Molecules | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 15 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.subject.keywordPlus | METAL-IONS | - |
dc.subject.keywordPlus | COPPER HOMEOSTASIS | - |
dc.subject.keywordPlus | ACTIVATED CARBON | - |
dc.subject.keywordPlus | RECENT PROGRESS | - |
dc.subject.keywordPlus | FLUORESCENT | - |
dc.subject.keywordPlus | HG2+ | - |
dc.subject.keywordPlus | CHEMOSENSOR | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | IRON | - |
dc.subject.keywordPlus | SENSITIVITY | - |
dc.subject.keywordAuthor | fluorescence | - |
dc.subject.keywordAuthor | bis(triazole)-conjugated naphthoquinolinedione | - |
dc.subject.keywordAuthor | Cu2+ sensing | - |
dc.subject.keywordAuthor | bio-imaging | - |
dc.subject.keywordAuthor | colorimetric | - |
dc.subject.keywordAuthor | ratio-metric | - |
dc.identifier.url | https://www.mdpi.com/1420-3049/27/3/785 | - |
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