Precipitation-Mediated PEGylation of Plant-Derived Nanovesicles
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Van Quy Nguyen | - |
dc.contributor.author | Um, Wooram | - |
dc.contributor.author | An, Jae Yoon | - |
dc.contributor.author | Joo, Hyeyeon | - |
dc.contributor.author | Choi, Young Chan | - |
dc.contributor.author | Jung, Jae Min | - |
dc.contributor.author | Choi, Ji Suk | - |
dc.contributor.author | You, Dong Gil | - |
dc.contributor.author | Cho, Yong Woo | - |
dc.contributor.author | Park, Jae Hyung | - |
dc.date.accessioned | 2022-07-18T01:20:01Z | - |
dc.date.available | 2022-07-18T01:20:01Z | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 1598-5032 | - |
dc.identifier.issn | 2092-7673 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/107975 | - |
dc.description.abstract | Recently, plant-derived nanovesicles have attracted interest in the field of regenerative medicine because of their abundant immune-regulatory RNAs and phytochemicals with cell proliferation activity. However, the poor stability and rapid clearance of vesicles remain major challenges in their clinical applications. Herein, we report a facile method for surface modification of plant-derived nanovesicles by precipitation in the presence of poly(ethylene glycol) (PEG). We confirmed that PEGylation of nanovesicles slightly increased the particle size and zeta potential values. Importantly, this simple precipitation method produced PEGylated nanovesicles without any quantitative or qualitative loss of internal contents. When dispersed in PBS (pH 7.4), PEGylated nanovesicles did not exhibit a significant change in size for 24 h, indicating their high stability. Overall, our precipitation-based method is a useful technique for PEGylation of plant-derived nanovesicles without loss of bioactivity. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국고분자학회 | - |
dc.title | Precipitation-Mediated PEGylation of Plant-Derived Nanovesicles | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.1007/s13233-022-0016-x | - |
dc.identifier.scopusid | 2-s2.0-85126123925 | - |
dc.identifier.wosid | 000764055800002 | - |
dc.identifier.bibliographicCitation | Macromolecular Research, v.30, no.2, pp 85 - 89 | - |
dc.citation.title | Macromolecular Research | - |
dc.citation.volume | 30 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 85 | - |
dc.citation.endPage | 89 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002811817 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.subject.keywordPlus | EXTRACELLULAR VESICLES | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | EXOSOMES | - |
dc.subject.keywordAuthor | polyethylene glycol (PEG) | - |
dc.subject.keywordAuthor | extracellular vesicles | - |
dc.subject.keywordAuthor | plant nanovesicles | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s13233-022-0016-x | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
55 Hanyangdeahak-ro, Sangnok-gu, Ansan, Gyeonggi-do, 15588, Korea+82-31-400-4269 sweetbrain@hanyang.ac.kr
COPYRIGHT © 2021 HANYANG UNIVERSITY. ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.