Neuroprotective Potential of Carnosine in Cerebrovascular Diseases
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Neelakandan, A. R. | - |
dc.contributor.author | Bae, Ok-Nam | - |
dc.contributor.author | Majid, Arshad | - |
dc.contributor.author | Burak, Caglayan A. | - |
dc.contributor.author | Rajanikant, G. K. | - |
dc.date.accessioned | 2022-07-18T01:22:30Z | - |
dc.date.available | 2022-07-18T01:22:30Z | - |
dc.date.issued | 2022-01 | - |
dc.identifier.issn | 1573-3149 | - |
dc.identifier.issn | 1573-3904 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/108035 | - |
dc.description.abstract | The growing prevalence, the risk of disabilities, and the lack of effective causal or disease-modifying therapies make cerebrovascular disorders a serious burden. Carnosine, an evolutionarily conserved endogenous dipeptide and over-the-counter food supplement, has a wealth of evidence exhibiting potentially neuroprotective effects. It is a natural, multi-functional, non-toxic anti-glycating antioxidant found in high concentrations in human and mammalian muscle and brain tissues. The physiological presence of carnosine in the brain, ability to cross the blood-brain barrier, and evidence from in vitro, and in vivo studies all point to it as a promising neurotherapeutic agent for cerebrovascular disorders. This review is intended to provide a detailed overview of the neuroprotective role of carnosine in cerebrovascular diseases and summarize existing evidence from cell and animal studies. | - |
dc.format.extent | 12 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | Neuroprotective Potential of Carnosine in Cerebrovascular Diseases | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1007/s10989-021-10342-5 | - |
dc.identifier.scopusid | 2-s2.0-85121147683 | - |
dc.identifier.wosid | 000729795900005 | - |
dc.identifier.bibliographicCitation | International Journal of Peptide Research and Therapeutics, v.28, no.1, pp 1 - 12 | - |
dc.citation.title | International Journal of Peptide Research and Therapeutics | - |
dc.citation.volume | 28 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 12 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.subject.keywordPlus | CHRONIC CEREBRAL HYPOPERFUSION | - |
dc.subject.keywordPlus | ISCHEMIC NEURONAL DAMAGE | - |
dc.subject.keywordPlus | WHITE-MATTER DAMAGE | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | CELL-DEATH | - |
dc.subject.keywordPlus | ENDOGENOUS NEUROPROTECTOR | - |
dc.subject.keywordPlus | INTRACEREBRAL HEMORRHAGE | - |
dc.subject.keywordPlus | SUBARACHNOID HEMORRHAGE | - |
dc.subject.keywordPlus | INDUCED NEUROTOXICITY | - |
dc.subject.keywordPlus | ENERGY-METABOLISM | - |
dc.subject.keywordAuthor | Carnosine | - |
dc.subject.keywordAuthor | Ischemic stroke | - |
dc.subject.keywordAuthor | Hemorrhagic stroke | - |
dc.subject.keywordAuthor | Vascular dementia | - |
dc.subject.keywordAuthor | Neuroprotection | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s10989-021-10342-5 | - |
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