Time-course trend and influencing factors for per- and polyfluoroalkyl substances in the breast milk of Korean mothers
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, J.H. | - |
dc.contributor.author | Moon, N. | - |
dc.contributor.author | Lee, J.-W. | - |
dc.contributor.author | Mehdi, Q. | - |
dc.contributor.author | Yun, M.-H. | - |
dc.contributor.author | Moon, H.-B. | - |
dc.date.accessioned | 2023-04-03T10:03:15Z | - |
dc.date.available | 2023-04-03T10:03:15Z | - |
dc.date.issued | 2023-01 | - |
dc.identifier.issn | 0045-6535 | - |
dc.identifier.issn | 1879-1298 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/111653 | - |
dc.description.abstract | Many studies have reported that neonates and infants are exposed to several per- and polyfluoroalkyl substances (PFASs) via breastfeeding; however, these studies have had small sample sizes. This study aimed to determine the concentrations and time-course trend of PFASs in breast milk and identify influencing factors governing PFAS concentrations. Between July and September (2018), 207 low-risk primiparous women were recruited from a lactation counseling clinic in Korea and their breast milk samples were tested for 14 PFASs, including four perfluoroalkyl sulfonic acids. A questionnaire survey, comprising 84 questions covering the women's demographic, obstetrical, dietary, lifestyle, behavioral, and neonatal information, was conducted to investigate associations. Twelve of the 14 PFASs were detectable in breast milk samples. Perfluorooctanesulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and perfluorodecanoic acid were detected in 100% of the samples, followed by perfluorohexanesulfonic acid (detection rate: 87%), perfluorononanoic acid (87%), and perfluorohexanoic acid (73%); the median concentrations were 0.05, 0.10, 0.031, 0.007, and 0.033 ng/mL, respectively. The PFAS concentrations in breast milk measured in our study were higher than those reported in other studies or countries. In 12 years, from 2007 to 18, the mean concentration of PFOA in breast milk increased by approximately three times (278%). The major factors associated with PFAS concentrations in the bivariate association analysis were body mass index; living area (non-metropolitan); neonatal age; and frequency of fish, ice cream, and canned food consumption. In the multiple regression model, fish consumption significantly influenced the PFOS concentrations in breast milk (β = 0.88, p = 0.033). Frequently, fish consumption has been analyzed as the main dietary factor related to PFOS concentration. Our findings suggest the need for a comprehensive cohort study on PFAS exposure and its association with infant health. © 2022 Elsevier Ltd | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier Ltd | - |
dc.title | Time-course trend and influencing factors for per- and polyfluoroalkyl substances in the breast milk of Korean mothers | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1016/j.chemosphere.2022.136688 | - |
dc.identifier.scopusid | 2-s2.0-85139872948 | - |
dc.identifier.wosid | 000915566200004 | - |
dc.identifier.bibliographicCitation | Chemosphere, v.310, pp 1 - 10 | - |
dc.citation.title | Chemosphere | - |
dc.citation.volume | 310 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 10 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.subject.keywordPlus | PERFLUOROALKYL SUBSTANCES | - |
dc.subject.keywordPlus | PERFLUORINATED COMPOUNDS | - |
dc.subject.keywordPlus | FISH CONSUMPTION | - |
dc.subject.keywordPlus | FRENCH WOMEN | - |
dc.subject.keywordPlus | EXPOSURE | - |
dc.subject.keywordPlus | SERUM | - |
dc.subject.keywordPlus | PFASS | - |
dc.subject.keywordPlus | CONTAMINANTS | - |
dc.subject.keywordPlus | ACIDS | - |
dc.subject.keywordPlus | CORD | - |
dc.subject.keywordAuthor | Fish consumption | - |
dc.subject.keywordAuthor | Infant | - |
dc.subject.keywordAuthor | Perfluoroalkyl substances | - |
dc.subject.keywordAuthor | Perfluorooctanesulfonic acid | - |
dc.subject.keywordAuthor | Perfluorooctanoic acid | - |
dc.subject.keywordAuthor | Polyfluoroalkyl substances | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0045653522031812?via%3Dihub | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
55 Hanyangdeahak-ro, Sangnok-gu, Ansan, Gyeonggi-do, 15588, Korea+82-31-400-4269 sweetbrain@hanyang.ac.kr
COPYRIGHT © 2021 HANYANG UNIVERSITY. ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.