L-Cysteine-Meditated Self-Assembled PtRu Derived Bimetallic Metal–Carbon Hybrid: An Excellent Peroxidase Mimics for Colorimetric and Fluorometric Detection of Hydrogen Peroxide and Cholesterol
DC Field | Value | Language |
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dc.contributor.author | Gupta, Pramod K. | - |
dc.contributor.author | Son, Seong Eun | - |
dc.contributor.author | Seong, Gi Hun | - |
dc.date.accessioned | 2023-08-16T08:31:13Z | - |
dc.date.available | 2023-08-16T08:31:13Z | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 2196-7350 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/114311 | - |
dc.description.abstract | Artificial enzymes have attracted considerable attention because of their significant advantages over natural enzymes. Herein, the authors report a simple hydrothermal strategy for producing a bimetallic metal — N-, S-doped carbon (NS-C@PtRu) hybrid derived from L-cysteine-mediated self-assembly of PtRu. The peroxidase-like activity and colloidal stability of the NS-C@PtRu are tuned by varying the amount of L-cysteine, the source material for the N-, S-doped carbon. The NS-C@PtRu exhibits good dispersibility, synergistic interactions (metal–metal, metal–carbon), non-metal (N, S) doping, more catalytic active sites, improved noble metallic catalyst performance, and high utilization efficiency. As an excellent peroxidase mimic, NS-C@PtRu catalyzes the oxidation of 3,3′,5′,5′-tetramethylbenzidine (TMB), and Amplex Red (AR) substrates, producing colorimetric and fluorometric signals that offer efficient detection of H2O2. Furthermore, colorimetric and fluorometric cholesterol detection is proposed by combining cholesterol oxidase-catalyzed cholesterol oxidation with NS-C@PtRu-catalyzed TMB/AR oxidation. The fluorometric cholesterol sensor exhibited a lower limit of detection of 1.4 µmol L−1 and rapid response, whereas the colorimetric sensor exhibited a wide detection range of 0.1–6 mmol L−1 and colorimetric changes that can be seen with the naked eyes. Both sensing methods demonstrated excellent selectivity and recovery in determining cholesterol in spiked human serum samples. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | John Wiley and Sons Ltd | - |
dc.title | L-Cysteine-Meditated Self-Assembled PtRu Derived Bimetallic Metal–Carbon Hybrid: An Excellent Peroxidase Mimics for Colorimetric and Fluorometric Detection of Hydrogen Peroxide and Cholesterol | - |
dc.type | Article | - |
dc.publisher.location | 미국 | - |
dc.identifier.doi | 10.1002/admi.202101115 | - |
dc.identifier.scopusid | 2-s2.0-85118886044 | - |
dc.identifier.wosid | 000716671500001 | - |
dc.identifier.bibliographicCitation | Advanced Materials Interfaces, v.8, no.23, pp 1 - 16 | - |
dc.citation.title | Advanced Materials Interfaces | - |
dc.citation.volume | 8 | - |
dc.citation.number | 23 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 16 | - |
dc.type.docType | 정기학술지(Article(Perspective Article포함)) | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.subject.keywordPlus | SILVER NANOPARTICLES | - |
dc.subject.keywordPlus | FLUORESCENCE SENSOR | - |
dc.subject.keywordPlus | GOLD NANOPARTICLES | - |
dc.subject.keywordPlus | MIMETIC ACTIVITY | - |
dc.subject.keywordPlus | HIGH-PERFORMANCE | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | OXIDASE | - |
dc.subject.keywordPlus | NANOCOMPOSITE | - |
dc.subject.keywordPlus | NANOZYME | - |
dc.subject.keywordPlus | GLUCOSE | - |
dc.subject.keywordAuthor | bimetallic materials | - |
dc.subject.keywordAuthor | cholesterol detection | - |
dc.subject.keywordAuthor | enzyme mimics | - |
dc.subject.keywordAuthor | H | - |
dc.subject.keywordAuthor | O-2 | - |
dc.subject.keywordAuthor | (2) detection | - |
dc.subject.keywordAuthor | hybrid structure | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1002/admi.202101115 | - |
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