Generation of a human iPSC line from a Parkinson's disease patient with a novel CHCHD2 mutation (p.R145Q)
DC Field | Value | Language |
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dc.contributor.author | Chen, Xiaona | - |
dc.contributor.author | Sun, Jing | - |
dc.contributor.author | Wang, Tian | - |
dc.contributor.author | Tang, Qingyuan | - |
dc.contributor.author | Su, Lu | - |
dc.contributor.author | Sun, Yimin | - |
dc.contributor.author | Chen, Liang | - |
dc.contributor.author | Seo, Hyemyung | - |
dc.contributor.author | Cheng, Tianlin | - |
dc.contributor.author | Wang, Jian | - |
dc.contributor.author | Song, Bin | - |
dc.date.accessioned | 2024-04-23T06:00:30Z | - |
dc.date.available | 2024-04-23T06:00:30Z | - |
dc.date.issued | 2024-06 | - |
dc.identifier.issn | 1873-5061 | - |
dc.identifier.issn | 1876-7753 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/118847 | - |
dc.description.abstract | Mutations in CHCHD2 have been reported to be associated with familial Parkinson's disease (PD). We generated a human induced pluripotent stem cell (hiPSC) line by reprogramming dermal fibroblasts from a PD patient harboring a novel CHCHD2 mutation (c.434G > A, p.R145Q). This line exhibited human embryonic stem cell (hESC)-like clonal morphology, expression of undifferentiated stem cell markers, a normal karyotype and trilineage differentiation capacity and thus the potential to serve as a model for further investigating the underlying molecular mechanisms of CHCHD2 function in PD. © 2024 The Authors | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier B.V. | - |
dc.title | Generation of a human iPSC line from a Parkinson's disease patient with a novel CHCHD2 mutation (p.R145Q) | - |
dc.type | Article | - |
dc.publisher.location | 네델란드 | - |
dc.identifier.doi | 10.1016/j.scr.2024.103419 | - |
dc.identifier.scopusid | 2-s2.0-85190477393 | - |
dc.identifier.wosid | 001231046000001 | - |
dc.identifier.bibliographicCitation | Stem Cell Research, v.77, pp 1 - 5 | - |
dc.citation.title | Stem Cell Research | - |
dc.citation.volume | 77 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 5 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Cell & Tissue Engineering | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S187350612400117X?via%3Dihub | - |
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