Facile Synthesis of 2-Amino-4-alkoxypyrimidines via Consecutive Nucleophilic Aromatic Substitution (SNAr) Reactions
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Juhyeon | - |
dc.contributor.author | Cho, Yong Seo | - |
dc.contributor.author | Min, Sun-Joon | - |
dc.date.accessioned | 2021-06-22T15:44:08Z | - |
dc.date.available | 2021-06-22T15:44:08Z | - |
dc.date.issued | 2016-12 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.issn | 1229-5949 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/12171 | - |
dc.description.abstract | A transition-metal-free and regioselective synthesis of a series of 2-amino-4-alkoxypyrimidines is described. The SNAr alkoxylation of 2,4-dichloropyrimidines regioselectively provided 2-chloro-4-alkoxypyrimidines, which were subsequently subject to the second SNAr amination with cyclic amines in the presence of triethylamine at high temperature to afford 2-amino-4-alkoxypyrimidines in good overall yield. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 대한화학회 | - |
dc.title | Facile Synthesis of 2-Amino-4-alkoxypyrimidines via Consecutive Nucleophilic Aromatic Substitution (SNAr) Reactions | - |
dc.type | Article | - |
dc.publisher.location | 대한민국 | - |
dc.identifier.doi | 10.1002/bkcs.11014 | - |
dc.identifier.scopusid | 2-s2.0-85003703938 | - |
dc.identifier.wosid | 000390270200018 | - |
dc.identifier.bibliographicCitation | Bulletin of the Korean Chemical Society, v.37, no.12, pp 1998 - 2008 | - |
dc.citation.title | Bulletin of the Korean Chemical Society | - |
dc.citation.volume | 37 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1998 | - |
dc.citation.endPage | 2008 | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002172604 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.subject.keywordPlus | CROSS-COUPLING REACTIONS | - |
dc.subject.keywordPlus | REGIOSELECTIVE 4-AMINO-DE-CHLORINATION | - |
dc.subject.keywordPlus | HETEROCYCLES | - |
dc.subject.keywordPlus | PYRIMIDINES | - |
dc.subject.keywordPlus | INHIBITOR | - |
dc.subject.keywordPlus | EFFICIENT | - |
dc.subject.keywordAuthor | 2-Amino-4-alkoxypyrimidines | - |
dc.subject.keywordAuthor | Nucleophilic aromatic substitution | - |
dc.subject.keywordAuthor | Regioselectivity | - |
dc.subject.keywordAuthor | Alkoxylation | - |
dc.subject.keywordAuthor | Amination | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/bkcs.11014 | - |
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