2D to 3D transformation of gold nanosheets on human adipose-derived α-elastin nanotemplates
- Authors
- Kim, Jae Dong; Han, Hwa Seung; Kim, Hye In; Choi, Ji Suk; Park, Jae Hyung; Kim, Jong Ho; Choi, Ki Young; Cho, Yong Woo
- Issue Date
- Mar-2021
- Publisher
- Korean Society of Industrial Engineering Chemistry
- Keywords
- Gold nanocrystals; Gold nanosheets; Human α-elastin; Shape-controlled synthesis; Surface-enhanced Raman scattering (SERS)
- Citation
- Journal of Industrial and Engineering Chemistry, v.95, pp 66 - 72
- Pages
- 7
- Indexed
- SCIE
SCOPUS
KCI
- Journal Title
- Journal of Industrial and Engineering Chemistry
- Volume
- 95
- Start Page
- 66
- End Page
- 72
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/1482
- DOI
- 10.1016/j.jiec.2020.12.004
- ISSN
- 1226-086X
1876-794X
- Abstract
- Controlling the morphology and surface properties of gold nanocrystals (AuNCs) can facilitate tailoring their localized surface plasmon resonance (LSPR) and surface-enhanced Raman scattering (SERS) properties for biomedical applications. However, the shape-controlled synthesis of AuNCs for bioapplications remains challenging, given its critical issues, such as the use of toxic reagents and multiple complicated steps. This study demonstrates the facile, biocompatible, and shape-controllable synthesis of AuNCs. This method employs human α-elastin (HαE) self-assemblies as a shape-directing template, reducing agent, and surfactant. Since HαE is a ubiquitous protein present in human tissue, it is non-toxic and non-immunogenic. This method is thus simple and biocompatible. Of particular note, the sheet-type HαE template enables the shape-controlled synthesis of AuNCs—gold nanoparticles, nanosheets, and a rose-flower-like nanostructure (AuRF) stacked with multiple nanosheets. Among the AuNCs, the AuRF exhibits unique optical and electromagnetic properties—an LSPR peak in the near-infrared (NIR) region and characteristic SERS peaks—given the rough surface with sharp edges. To the best of our knowledge, this is the first report on the biosynthesis of AuNCs using human-derived biomolecules such as HαE. The shape-controllable biosynthesis of AuNCs based on HαE may open up possibilities for a wide range of biomedical applications of AuNCs. © 2020 The Korean Society of Industrial and Engineering Chemistry
- Files in This Item
-
Go to Link
- Appears in
Collections - COLLEGE OF ENGINEERING SCIENCES > DEPARTMENT OF MATERIALS SCIENCE AND CHEMICAL ENGINEERING > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/1482)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.