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Combined phototherapy in anti-cancer treatment: therapeutics design and perspectives
- Authors
- Tran, Tuan Hiep; Thapa, Raj Kumar; Nguyen, Hanh Thuy; Pham, Tung Thanh; Ramasamy, Thiruganesh; Kim, Dong Shik; Yong, Chul Soon; Kim, Jong Oh; Choi, Han-Gon
- Issue Date
- Aug-2016
- Publisher
- Springer Netherlands
- Keywords
- Hyperthermia; Nanocarriers; Photodynamic; Photosensitiser; Photothermal
- Citation
- Journal of Pharmaceutical Investigation, v.46, no.6, pp 505 - 517
- Pages
- 13
- Indexed
- SCOPUS
KCI
- Journal Title
- Journal of Pharmaceutical Investigation
- Volume
- 46
- Number
- 6
- Start Page
- 505
- End Page
- 517
- ISSN
- 2093-5552
2093-6214
- Abstract
- Photodynamic (PDT) and photothermal (PTT) therapy are proven effective strategies for the treatment of cancer. PDT, a photochemistry-based therapy, utilises light energy based photosensitiser for the production of cytotoxic species via electron transfer to biological substrates and potential excitation or energy transfer to molecular oxygen. On the other hand, PTT utilises substances that can convert light energy into heat for efficient tumour ablation. This review provides an insight into the current research investigations of different nanocarriers utilising the synergistic effects of PTT and PDT for anticancer therapy. © 2016, The Korean Society of Pharmaceutical Sciences and Technology.
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Related Researcher
- Choi, Han Gon
- COLLEGE OF PHARMACY (DEPARTMENT OF PHARMACY)