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STRESS-FREE ALIGNMENT OF CELLS ON HIGHLY-ALIGNED COLLAGEN NANOFIBERS

Authors
Lee, W.C.Nam, E.Takeuchi, S.
Issue Date
Oct-2015
Publisher
The Chemical and Biological Microsystems Society (CBMS)
Keywords
Alignment; Collagen nanofibers; Cyclic stretch
Citation
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), pp.571 - 572
Indexed
SCOPUS
Journal Title
19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS)
Start Page
571
End Page
572
URI
https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/16923
Abstract
This paper presents the optimization of collagen nanofiber alignments in 2D substrates and applies the optimized substrates for aligning cells without mechanical stresses during cultivation. In this work, we show that 1) the collagen nanofiber alignment is optimized by changing of cyclic stretch conditions such as frequency, strain, and time, and 2) the fabricated collagen substrate aligns cells without any mechanical stresses during cultivation, thus even enabling corneal stromal cell alignments which are known to be difficult using in-vitro cultivation. © 15CBMS-0001.
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COLLEGE OF ENGINEERING SCIENCES > DEPARTMENT OF MECHANICAL ENGINEERING > 1. Journal Articles

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ERICA 공학대학 (DEPARTMENT OF MECHANICAL ENGINEERING)
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