STRESS-FREE ALIGNMENT OF CELLS ON HIGHLY-ALIGNED COLLAGEN NANOFIBERS
- Authors
- Lee, W.C.; Nam, E.; Takeuchi, S.
- Issue Date
- Oct-2015
- Publisher
- The Chemical and Biological Microsystems Society (CBMS)
- Keywords
- Alignment; Collagen nanofibers; Cyclic stretch
- Citation
- 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), pp.571 - 572
- Indexed
- SCOPUS
- Journal Title
- 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS)
- Start Page
- 571
- End Page
- 572
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/16923
- Abstract
- This paper presents the optimization of collagen nanofiber alignments in 2D substrates and applies the optimized substrates for aligning cells without mechanical stresses during cultivation. In this work, we show that 1) the collagen nanofiber alignment is optimized by changing of cyclic stretch conditions such as frequency, strain, and time, and 2) the fabricated collagen substrate aligns cells without any mechanical stresses during cultivation, thus even enabling corneal stromal cell alignments which are known to be difficult using in-vitro cultivation. © 15CBMS-0001.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - COLLEGE OF ENGINEERING SCIENCES > DEPARTMENT OF MECHANICAL ENGINEERING > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/16923)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.