Single-carbon discrimination by selected peptides for individual detection of volatile organic compounds
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ju, Soomi | - |
dc.contributor.author | Lee, Ki-Young | - |
dc.contributor.author | Min, Sun-Joon | - |
dc.contributor.author | Yoo, Yong Kyoung | - |
dc.contributor.author | Hwang, Kyo Seon | - |
dc.contributor.author | Kim, Sang Kyung | - |
dc.contributor.author | Yi, Hyunjung | - |
dc.date.accessioned | 2021-06-22T20:22:45Z | - |
dc.date.available | 2021-06-22T20:22:45Z | - |
dc.date.issued | 2015-03 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/18786 | - |
dc.description.abstract | Although volatile organic compounds (VOCs) are becoming increasingly recognized as harmful agents and potential biomarkers, selective detection of the organic targets remains a tremendous challenge. Among the materials being investigated for target recognition, peptides are attractive candidates because of their chemical robustness, divergence, and their homology to natural olfactory receptors. Using a combinatorial peptide library and either a graphitic surface or phenyl-terminated self-assembled monolayer as relevant target surfaces, we successfully selected three interesting peptides that differentiate a single carbon deviation among benzene and its analogues. The heterogeneity of the designed target surfaces provided peptides with varying affinity toward targeted molecules and generated a set of selective peptides that complemented each other. Microcantilever sensors conjugated with each peptide quantitated benzene, toluene and xylene to sub-ppm levels in real time. The selection of specific receptors for a group of volatile molecules will provide a strong foundation for general approach to individually monitoring VOCs. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Nature Publishing Group | - |
dc.title | Single-carbon discrimination by selected peptides for individual detection of volatile organic compounds | - |
dc.type | Article | - |
dc.publisher.location | 영국 | - |
dc.identifier.doi | 10.1038/srep09196 | - |
dc.identifier.scopusid | 2-s2.0-84924942348 | - |
dc.identifier.wosid | 000351230000007 | - |
dc.identifier.bibliographicCitation | Scientific Reports, v.5, pp 1 - 6 | - |
dc.citation.title | Scientific Reports | - |
dc.citation.volume | 5 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 6 | - |
dc.type.docType | Article | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | PULMONARY-DISEASES | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | BIOMARKERS | - |
dc.subject.keywordPlus | BENZENE | - |
dc.subject.keywordPlus | MICROCANTILEVER | - |
dc.subject.keywordPlus | NANOSTRUCTURES | - |
dc.subject.keywordPlus | EXPLOSIVES | - |
dc.subject.keywordPlus | LEUKEMIA | - |
dc.subject.keywordPlus | BINDING | - |
dc.identifier.url | https://www.nature.com/articles/srep09196 | - |
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