세포바깥소포체와 신경계질환Extracellular Vesicles and Neurological Diseases
- Other Titles
- Extracellular Vesicles and Neurological Diseases
- Authors
- 호동환; 서혜명; 손일홍; 설원기
- Issue Date
- May-2015
- Publisher
- 대한신경과학회
- Keywords
- Extracellular vesicle; Exosome; Biomarker
- Citation
- 대한신경과학회지, v.33, no.2, pp 75 - 81
- Pages
- 7
- Indexed
- KCI
- Journal Title
- 대한신경과학회지
- Volume
- 33
- Number
- 2
- Start Page
- 75
- End Page
- 81
- URI
- https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/20129
- DOI
- 10.17340/jkna.2015.2.1
- ISSN
- 1225-7044
2288-985X
- Abstract
- Extracellular vesicles (EVs) are small membranous vesicles that are secreted by various types of cells into biofluid or culture medium. EVs contain deoxyribonucleic acids, messenger ribonucleic acids (RNAs), microRNAs, lipids, and proteins derived from its cells of origin and can transfer those molecules to other targeted cells. Therefore, EVs can play important roles in intercellular communication. The findings of recent studies suggest that EVs can be used to spread protein aggregates in various neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease. In addition, it has been recognized that EVs can be used as a material for detecting biomarkers for such diseases or as a therapeutic tool.
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