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Engineering of a lipid-polymer nanoarchitectural platform for highly effective combination therapy of doxorubicin and irinotecan
- Authors
- Ramasamy, T.; Ruttala, H. B.; Choi, J. Y.; Tran, T. H.; Kim, J. H.; Ku, S. K.; Choi, H. G.; Yong, C. S.; Kim, J. O.
- Issue Date
- Feb-2015
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.51, no.26, pp.5758 - 5761
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 51
- Number
- 26
- Start Page
- 5758
- End Page
- 5761
- ISSN
- 1359-7345
- Abstract
- We developed a highly stable lipid-polymer nanoarchitectural platform for effective combination therapy of doxorubicin and irinotecan in the polyelectrolyte complex nanoparticle core, followed by incorporation of the whole assembly into a lecithin bilayer. It shows great potential for the treatment of a broad range of cancers.
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Related Researcher
- Choi, Han Gon
- COLLEGE OF PHARMACY (DEPARTMENT OF PHARMACY)