Recent Submissions

• Gypenoside L inhibits hepatocellular carcinoma by targeting the SREBP2-HMGCS1 axis and enhancing immune response
• Rapid investigating of phase I metabolites of SR9009 in vitro horse liver microsomes via feature-based molecular networking approach: Potential applications in doping control
• Design and synthesis of selective and potential PLK1-targeting inhibitors for NSCLC treatment
• The promising therapeutic potential of carbamate JNK3 inhibitors for Alzheimer's disease
• Synthesis of hydroxynaphthylcarbazide derivatives and their activity to inhibit prion protein aggregation
• Molecular insights into regulatory RNAs in the cellular machinery
• Modification of microenvironmental pH of nanoparticles for enhanced solubility and oral bioavailability of poorly water-soluble celecoxib
• The BTLA-HVEM axis restricts CAR T cell efficacy in cancer
• G Protein-Coupled Estrogen Receptor-Mediated Anti-Inflammatory and Mucosal Healing Activity of a Trimethylpyridinol Analogue in Inflammatory Bowel Disease
• CYR61 as a potential therapeutic target in sorafenib-resistant hepatocellular carcinoma
• Gaining Insights into Key Structural Hotspots within the Allosteric Binding Pockets of Protein Kinases
• Safety assessment of cocamidopropyl betaine, a cosmetic ingredient
• Streamlined measurement of chimeric antigen receptor T-cell concentration, size, viability and two-color phenotyping during manufacturing
• Guidelines for Manufacturing and Application of Organoids: Heart
• Peroxidase-Mimicking Iron-Based Single-Atom Upconversion Photocatalyst for Enhancing Chemodynamic Therapy
• Therapeutic potential of ginseng leaf extract in inhibiting mast cell-mediated allergic inflammation and atopic dermatitis-like skin inflammation in DNCB-treated mice
• Design and Synthesis of PLK1 Inhibitors as Therapeutics for NSCLC
• PLK1-mediated phosphorylation of FoxM1 promotes epithelial-mesenchymal transition.
• In Vivo Studies on Mouse Models Demonstrate the Potential Efficacy of Carbamate JNK3 Inhibitors as Therapeutic Candidates for Alzheimer's Disease
• Design and synthesis of CD73 inhibitors for cancer immunotheraphy : nucleotide and non-nucleotide approaches.