Swimming exercise stimulates neuro-genesis in the subventricular zone via increase in synapsin i and nerve growth factor levels
DC Field | Value | Language |
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dc.contributor.author | Chae, Chang-hun | - |
dc.contributor.author | Jung, Sung-lim | - |
dc.contributor.author | An, Sang-hyun | - |
dc.contributor.author | Park, B-Y | - |
dc.contributor.author | Kim, Tae-woon | - |
dc.contributor.author | Wang, S-W | - |
dc.contributor.author | Kim, Jae-hyoo | - |
dc.contributor.author | Lee, H-C | - |
dc.contributor.author | Kim, Hyun-tae | - |
dc.date.accessioned | 2021-06-23T01:44:16Z | - |
dc.date.available | 2021-06-23T01:44:16Z | - |
dc.date.created | 2021-01-21 | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0860-021X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/25889 | - |
dc.description.abstract | In this study, we investigated the effects of 8-weeks of swimming exercise on neurogenesis in the subventricular zone (SVZ) and on the levels of nerve growth factor (NGF) and synapsin I protein in the olfactory bulb (OB) of adult rats at a series of relevant time points (2 days, 1 week, 2 weeks, 4 weeks, 3 months, and 6 months). Ninety-six male Sprague Dawley rats were divided into 2 groups: (1) a control group (COG; n = 48, n = 8 for each time point) and (2) a swimming exercise group (SEG; total n = 48; n = 8 for each time point). SEG performed swimming exercise for 5 days per week over a period of 8 weeks. We found that the number of 5-bromo-2'-deoxyuridine-5'-monophosphate (BrdU)- and doublecortin (DCX)-positive cells was significantly higher in SEG than in COG at all time points (Day 2, Week 1, Week 2, Week 4, Month 3, and Month 6; p < 0.001). Furthermore, NGF and synapsin I protein levels were significantly higher in SEG on Day 2, and Weeks 1, 2, and 4 than in COG (p < 0.05 for each time point). Our findings suggest that regular swimming exercise in adult rats increases neurogenesis, neuronal survival, and neuronal maintenance in the SVZ; furthermore, swimming exercise increases the levels of NGF and synapsin I in the OB. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Instytut Sportu/Institute of Sport | - |
dc.title | Swimming exercise stimulates neuro-genesis in the subventricular zone via increase in synapsin i and nerve growth factor levels | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Park, B-Y | - |
dc.identifier.doi | 10.5604/20831862.1132130 | - |
dc.identifier.scopusid | 2-s2.0-84942101511 | - |
dc.identifier.wosid | 000347436700010 | - |
dc.identifier.bibliographicCitation | Biology of Sport, v.31, no.4, pp.309 - 314 | - |
dc.relation.isPartOf | Biology of Sport | - |
dc.citation.title | Biology of Sport | - |
dc.citation.volume | 31 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 309 | - |
dc.citation.endPage | 314 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Sport Sciences | - |
dc.relation.journalWebOfScienceCategory | Sport Sciences | - |
dc.subject.keywordPlus | LONG-TERM SURVIVAL | - |
dc.subject.keywordPlus | OLFACTORY-BULB | - |
dc.subject.keywordPlus | ENRICHED ENVIRONMENT | - |
dc.subject.keywordPlus | HIPPOCAMPAL | - |
dc.subject.keywordPlus | NEURONS | - |
dc.subject.keywordPlus | DEPRIVATION | - |
dc.subject.keywordPlus | NGF | - |
dc.subject.keywordPlus | APOPTOSIS | - |
dc.subject.keywordPlus | DAMAGE | - |
dc.subject.keywordPlus | DEATH | - |
dc.subject.keywordAuthor | physical training | - |
dc.subject.keywordAuthor | progenitor cells | - |
dc.subject.keywordAuthor | olfactory bulb | - |
dc.subject.keywordAuthor | neurotrophic factors | - |
dc.subject.keywordAuthor | brain | - |
dc.subject.keywordAuthor | rats | - |
dc.identifier.url | https://www.proquest.com/docview/2447236888?accountid=11283 | - |
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