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Self-Assembly Behaviors of a Penta-Phenylene Maltoside and Its Application for Membrane Protein Study

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dc.contributor.authorEhsan, Muhammad-
dc.contributor.authorKumar, Ashwani-
dc.contributor.authorMortensen, Jonas S.-
dc.contributor.authorDu, Yang-
dc.contributor.authorHariharan, Parameswaran-
dc.contributor.authorKumar, Kaavya K.-
dc.contributor.authorHa, Betty-
dc.contributor.authorByrne, Bernadette-
dc.contributor.authorGuan, Lan-
dc.contributor.authorKobilka, Brian K.-
dc.contributor.authorLoland, Claus J.-
dc.contributor.authorChae, Pil Seok-
dc.date.accessioned2021-06-22T10:01:46Z-
dc.date.available2021-06-22T10:01:46Z-
dc.date.created2021-01-21-
dc.date.issued2019-06-
dc.identifier.issn1861-4728-
dc.identifier.urihttps://scholarworks.bwise.kr/erica/handle/2021.sw.erica/2842-
dc.description.abstractWe prepared an amphiphile with a penta-phenylene lipophilic group and a branched trimaltoside head group. This new agent, designated penta-phenylene maltoside (PPM), showed a marked tendency to self-assembly into micelles via strong aromatic-aromatic interactions in aqueous media, as evidenced by H-1 NMR spectroscopy and fluorescence studies. When utilized for membrane protein studies, this new agent was superior to DDM, a gold standard conventional detergent, in stabilizing multiple proteins long term. The ability of this agent to form aromatic-aromatic interactions is likely responsible for enhanced protein stabilization when associated with a target membrane protein.-
dc.language영어-
dc.language.isoen-
dc.publisherWiley - V C H Verlag GmbbH & Co.-
dc.titleSelf-Assembly Behaviors of a Penta-Phenylene Maltoside and Its Application for Membrane Protein Study-
dc.typeArticle-
dc.contributor.affiliatedAuthorChae, Pil Seok-
dc.identifier.doi10.1002/asia.201900224-
dc.identifier.scopusid2-s2.0-85064174286-
dc.identifier.wosid000470021300006-
dc.identifier.bibliographicCitationChemistry - An Asian Journal, v.14, no.11, pp.1926 - 1931-
dc.relation.isPartOfChemistry - An Asian Journal-
dc.citation.titleChemistry - An Asian Journal-
dc.citation.volume14-
dc.citation.number11-
dc.citation.startPage1926-
dc.citation.endPage1931-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusBETA(2)-ADRENERGIC RECEPTOR-
dc.subject.keywordPlusAMPHIPHILES-
dc.subject.keywordPlusDETERGENT-
dc.subject.keywordPlusSOLUBILIZATION-
dc.subject.keywordPlusSTABILIZATION-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordPlusMICELLAR-
dc.subject.keywordPlusINSIGHTS-
dc.subject.keywordAuthoramphiphiles-
dc.subject.keywordAuthormembrane proteins-
dc.subject.keywordAuthormicelles-
dc.subject.keywordAuthormolecular design-
dc.subject.keywordAuthorprotein stability-
dc.subject.keywordAuthorself-assembly-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/10.1002/asia.201900224-
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ERICA 공학대학 (DEPARTMENT OF BIONANO ENGINEERING)
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