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Vasorelaxant Prenylated Flavonoids from the Roots of Sophora flavescens
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Chul Young | - |
| dc.contributor.author | Kim, Hyun Jung | - |
| dc.contributor.author | Kim, Kyeong-Man | - |
| dc.contributor.author | Oak, Min-Ho | - |
| dc.date.accessioned | 2021-06-23T04:04:30Z | - |
| dc.date.available | 2021-06-23T04:04:30Z | - |
| dc.date.issued | 2013-02 | - |
| dc.identifier.issn | 0916-8451 | - |
| dc.identifier.issn | 1347-6947 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/28876 | - |
| dc.description.abstract | Bioassay-guided fractionation of the methanol extract from the root of Sophora flaivscens led to the isolation of eight known prenylated flavonoids responsible for the vasorelaxation activity in porcine coronary arteries. Among them, kushenol N and 5-methylsophoraflavanone B strongly induced the relaxation of porcine coronary arteries with respective ED50 values of 8.6 and 12.4 mu m. This activity and the results of a high-performance liquid chromatographic analysis suggest that kushenol N and 5-methylsophoraflavanone B could be active markers in the S. flavescens extract for vasorelaxation activity. | - |
| dc.format.extent | 3 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | TAYLOR & FRANCIS LTD | - |
| dc.title | Vasorelaxant Prenylated Flavonoids from the Roots of Sophora flavescens | - |
| dc.type | Article | - |
| dc.publisher.location | 영국 | - |
| dc.identifier.doi | 10.1271/bbb.120739 | - |
| dc.identifier.scopusid | 2-s2.0-84875420732 | - |
| dc.identifier.wosid | 000316092600032 | - |
| dc.identifier.bibliographicCitation | BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, v.77, no.2, pp 395 - 397 | - |
| dc.citation.title | BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | - |
| dc.citation.volume | 77 | - |
| dc.citation.number | 2 | - |
| dc.citation.startPage | 395 | - |
| dc.citation.endPage | 397 | - |
| dc.type.docType | Article | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | sci | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
| dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalResearchArea | Food Science & Technology | - |
| dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
| dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
| dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
| dc.subject.keywordPlus | BIOLOGICAL EVALUATION | - |
| dc.subject.keywordPlus | AGENTS | - |
| dc.subject.keywordPlus | FLAVANONES | - |
| dc.subject.keywordPlus | MECHANISM | - |
| dc.subject.keywordPlus | EXTRACT | - |
| dc.subject.keywordAuthor | vasorelaxation activity | - |
| dc.subject.keywordAuthor | Sophora flavescens | - |
| dc.subject.keywordAuthor | prenylated flavonoid | - |
| dc.subject.keywordAuthor | kushenol N | - |
| dc.subject.keywordAuthor | 5-methylsophoraflavanone B | - |
| dc.identifier.url | https://www.tandfonline.com/doi/abs/10.1271/bbb.120739 | - |
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- Kim, Chul Young
- COLLEGE OF PHARMACY (DEPARTMENT OF PHARMACY)