Atomically-tailored graphene oxide displaying enhanced fluorescence for the improved optical sensing of MMP-2
DC Field | Value | Language |
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dc.contributor.author | Yang, Jin-Kyoung | - |
dc.contributor.author | Hwang, In-Jun | - |
dc.contributor.author | Jeon, Su-Ji | - |
dc.contributor.author | Ju, Jong-Min | - |
dc.contributor.author | Kim, Hye-In | - |
dc.contributor.author | Yim, DaBin | - |
dc.contributor.author | Lee, Yoon-Sik | - |
dc.contributor.author | Kim, Jong-Ho | - |
dc.date.accessioned | 2021-06-22T10:20:56Z | - |
dc.date.available | 2021-06-22T10:20:56Z | - |
dc.date.created | 2021-01-21 | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 0925-4005 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/3339 | - |
dc.description.abstract | Modulation of the optical properties of two-dimensional nanomaterials is a crucial step to improve their sensing performance for the optical detection of target molecules of interest. Here, we report a mild, simple and effective approach for heteroatoms-doping of graphene oxide (GO) without size alteration, resulting in enhanced fluorescence properties. Sulfur and nitrogen atoms were chemically doped onto the basal plane of GO (NSGO) via a sonic wave-assisted reaction with cysteine as an S and N dopant under acidic conditions at room temperature. As-prepared NSGO retained the same lateral size as pristine GO, but possessed a large proportion of thiopyran sulfur and pyrrolic nitrogen. In addition, NSGO exhibited highly enhanced fluorescence with strong resistance to the pH and polarity of solution. Mechanistic investigation suggested that S-doping was essential for the improved fluorescence properties of NSGO. Finally, to investigate the effect of heteroatoms-doping on sensing performance, fluorescent NSGO was employed as a fluorescent biosensor for the detection of matrix metalloproteinases 2 (MMP-2) via a peptide-induced assembly and self-quenching principle. As compared to pristine GO, NSGO assemblies exhibited more significant fluorescence quenching, but upon addition of MMP-2, the NSGO assemblies were disassembled, leading to the higher restoration of the quenched fluorescence, eventually resulting in the more sensitive detection of MMP-2. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Elsevier BV | - |
dc.title | Atomically-tailored graphene oxide displaying enhanced fluorescence for the improved optical sensing of MMP-2 | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jong-Ho | - |
dc.identifier.doi | 10.1016/j.snb.2018.12.100 | - |
dc.identifier.scopusid | 2-s2.0-85059477486 | - |
dc.identifier.wosid | 000460404100062 | - |
dc.identifier.bibliographicCitation | Sensors and Actuators, B: Chemical, v.284, pp.485 - 493 | - |
dc.relation.isPartOf | Sensors and Actuators, B: Chemical | - |
dc.citation.title | Sensors and Actuators, B: Chemical | - |
dc.citation.volume | 284 | - |
dc.citation.startPage | 485 | - |
dc.citation.endPage | 493 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.subject.keywordPlus | NITROGEN-DOPED GRAPHENE | - |
dc.subject.keywordPlus | QUANTUM DOTS | - |
dc.subject.keywordPlus | MATRIX METALLOPROTEINASES | - |
dc.subject.keywordPlus | CARBON DOTS | - |
dc.subject.keywordPlus | PHOTOLUMINESCENCE | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | SULFUR | - |
dc.subject.keywordPlus | ARRAYS | - |
dc.subject.keywordAuthor | Graphene oxide | - |
dc.subject.keywordAuthor | Heteroatom doping | - |
dc.subject.keywordAuthor | MMP-2 | - |
dc.subject.keywordAuthor | Optical biosensor | - |
dc.subject.keywordAuthor | Sonic wave-assisted reaction | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0925400518322196?via%3Dihub | - |
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