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Protective effects of cleavage agents on INS-1 cells against h-IAPP-induced apoptosis
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Jeong, Keunhong | - |
| dc.contributor.author | Cho, Hye Rim | - |
| dc.contributor.author | Choi, Seung Hong | - |
| dc.contributor.author | Park, Yangki | - |
| dc.contributor.author | Chae, Pil Seok | - |
| dc.date.accessioned | 2021-06-23T08:06:49Z | - |
| dc.date.available | 2021-06-23T08:06:49Z | - |
| dc.date.created | 2021-01-21 | - |
| dc.date.issued | 2012-01 | - |
| dc.identifier.issn | 1359-7345 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/33891 | - |
| dc.description.abstract | Cleavage agents showed cleavage yields as much as 9-14%, which does not sufficiently support the agents' protection of beta-cells from the cytotoxicity of h-IAPP. INS-1 cell tests were carried out to better understand the potential of using these cleavage agents as drug candidates. This study provides the firm basis for clinical applicability of these cleavage agents. | - |
| dc.language | 영어 | - |
| dc.language.iso | en | - |
| dc.publisher | Royal Society of Chemistry | - |
| dc.title | Protective effects of cleavage agents on INS-1 cells against h-IAPP-induced apoptosis | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Chae, Pil Seok | - |
| dc.identifier.doi | 10.1039/c1cc16293d | - |
| dc.identifier.scopusid | 2-s2.0-83455186578 | - |
| dc.identifier.wosid | 000299019200032 | - |
| dc.identifier.bibliographicCitation | Chemical Communications, v.48, no.4, pp.588 - 590 | - |
| dc.relation.isPartOf | Chemical Communications | - |
| dc.citation.title | Chemical Communications | - |
| dc.citation.volume | 48 | - |
| dc.citation.number | 4 | - |
| dc.citation.startPage | 588 | - |
| dc.citation.endPage | 590 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
| dc.subject.keywordPlus | IMAGING AGENT | - |
| dc.subject.keywordPlus | HIGH-AFFINITY | - |
| dc.subject.keywordPlus | ISLET | - |
| dc.subject.keywordPlus | CYTOTOXICITY | - |
| dc.subject.keywordPlus | DERIVATIVES | - |
| dc.subject.keywordPlus | OLIGOMERS | - |
| dc.subject.keywordPlus | BINDING | - |
| dc.subject.keywordPlus | MODEL | - |
| dc.subject.keywordPlus | MASS | - |
| dc.identifier.url | https://pubs.rsc.org/en/content/articlelanding/2012/CC/C1CC16293D | - |
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Related Researcher
- Chae, Pil Seok
- ERICA 첨단융합대학 (ERICA 바이오나노공학전공)