Fluorescence tunable thiophene-bis(benzimidazole)-based probes for a cascade trace detection of Hg2+ and lysine: A molecular switch mimic
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kumar, Ashwani | - |
dc.contributor.author | Chae, Pil Seok | - |
dc.date.accessioned | 2021-06-22T10:22:29Z | - |
dc.date.available | 2021-06-22T10:22:29Z | - |
dc.date.created | 2021-01-21 | - |
dc.date.issued | 2019-02 | - |
dc.identifier.issn | 0925-4005 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/3487 | - |
dc.description.abstract | Six thiophene-bis(benzimidazole)-based molecular probes with tunable fluorescence emission were synthesized for selective Hg2+ detection. Probe 1 contains a thiophene-bis(benzimidazole) unit without an appendage, while probes 2-4 have multiple appendages on benzimidazole rings of the core and probe 6/7 has two biphenyl appendages on the thiophene ring. Fluorescence emissions of all these probes were selectively quenched upon Hg2+ addition, but probe 7 provided the most sensitive detection of Hg2+, giving the highest association constant (K-a (7) = 2.38 x 10(6) M-1) and the lowest observed and calculated limit of detections (LODs) (5 nM and 0.047 pM, respectively). Thus, the probe 7-Hg2+ complex was further tested for detection of a biomolecule as a next step. Among the various biomolecules tested (including amino acids), L-lysine (Lys) uniquely showed a full restoration of the fluorescence intensity of [probe 7 + Hg2+ (1:2)]-complex to the level of the free probe, with an LOD of 5 nM. Thus, a cascade detection of Hg2+ and Lys was attained by probe 7 via selective quenching and recovering of the fluorescence intensity, which enables us to build an "ON-OFF-ON" switch and logic gate at a molecular level. The current system was fully studied by various analytical methods such as UV-vis, fluorescence, and H-1 NMR spectroscopies, IR, FE-SEM images, and DFT calculations. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | Elsevier BV | - |
dc.title | Fluorescence tunable thiophene-bis(benzimidazole)-based probes for a cascade trace detection of Hg2+ and lysine: A molecular switch mimic | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Chae, Pil Seok | - |
dc.identifier.doi | 10.1016/j.snb.2018.11.023 | - |
dc.identifier.scopusid | 2-s2.0-85056643408 | - |
dc.identifier.wosid | 000455021500115 | - |
dc.identifier.bibliographicCitation | Sensors and Actuators, B: Chemical, v.281, pp.933 - 944 | - |
dc.relation.isPartOf | Sensors and Actuators, B: Chemical | - |
dc.citation.title | Sensors and Actuators, B: Chemical | - |
dc.citation.volume | 281 | - |
dc.citation.startPage | 933 | - |
dc.citation.endPage | 944 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.subject.keywordPlus | HIGHLY SELECTIVE DETECTION | - |
dc.subject.keywordPlus | MERCURY II IONS | - |
dc.subject.keywordPlus | AQUEOUS-MEDIA | - |
dc.subject.keywordPlus | METAL-IONS | - |
dc.subject.keywordPlus | COLORIMETRIC RESPONSE | - |
dc.subject.keywordPlus | SILVER NANOPARTICLES | - |
dc.subject.keywordPlus | MULTIANALYTE SENSOR | - |
dc.subject.keywordPlus | ON PROBE | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | METHYLMERCURY | - |
dc.subject.keywordAuthor | Thiophene-bis(benzimidazole) | - |
dc.subject.keywordAuthor | Hg2+ | - |
dc.subject.keywordAuthor | Lysine | - |
dc.subject.keywordAuthor | ON-OFF-ON | - |
dc.subject.keywordAuthor | Switch | - |
dc.subject.keywordAuthor | Logic gate | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0925400518319774?via%3Dihub | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
55 Hanyangdeahak-ro, Sangnok-gu, Ansan, Gyeonggi-do, 15588, Korea+82-31-400-4269 sweetbrain@hanyang.ac.kr
COPYRIGHT © 2021 HANYANG UNIVERSITY. ALL RIGHTS RESERVED.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.