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New synthetic route to N-tocopherol derivatives: synthesis of pyrrolopyridinol analogue of alpha-tocopherol from pyridoxine

Authors
Nam, Tae-gyuKu, Jin-MoPark, Hyeung-geunPorter, Ned A.Jeong, Byeong-Seon
Issue Date
Mar-2011
Publisher
ROYAL SOC CHEMISTRY
Keywords
pyridine derivative; chemistry; synthesis; Pyridines; Phase-transfer catalytic alkylation; Synthetic routes; Hydroxylation; hydroxylation; Stereoisomerism; Pyrroles; alpha tocopherol; alpha-Tocopherol; Pyridoxine; article; pyridoxine; stereoisomerism; pyr
Citation
ORGANIC & BIOMOLECULAR CHEMISTRY, v.9, no.6, pp.1749 - 1755
Indexed
SCIE
SCOPUS
Journal Title
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume
9
Number
6
Start Page
1749
End Page
1755
URI
https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/39186
DOI
10.1039/c0ob00991a
ISSN
1477-0520
Abstract
A new synthetic route to pyrrolopyridinol antioxidants from easily accessible pyridoxine was developed which includes phase-transfer catalytic alkylation and intramolecular Cu(I)-catalyzed amination as key steps.
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