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Biomarker analysis of rat livers exposed to different toxic pollutants (VOCs and PAHs) using an antibody array
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Eung-Yoon | - |
| dc.contributor.author | Lee, Mi-Young | - |
| dc.contributor.author | Hwang, Seung Yong | - |
| dc.contributor.author | Kang, In-Cheol | - |
| dc.date.accessioned | 2021-06-23T14:05:58Z | - |
| dc.date.available | 2021-06-23T14:05:58Z | - |
| dc.date.issued | 2010-09 | - |
| dc.identifier.issn | 1976-0280 | - |
| dc.identifier.issn | 2092-7843 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/40414 | - |
| dc.description.abstract | We have developed an antibody microarray chip for biomarker analysis in rat livers exposed to five different toxic pollutants: volatile organic compounds (VOCs), dichloromethane, ethylbenzene, and trichloroethylene; and polycyclic aromatic hydrocarbons (PAHs), benzoanthracene and phenanthrene. The antibody chip consisted of antibodies against different biomarkers: alpha-2 μ globulin, glutathione S transferase (GST)-α, Hemoglobin β, and Phenylalanine hydroxylase. VOC- and PAH-treated rat livers showed differential expression patterns of the biomarker proteins. These results demonstrate that a protein chipbased antibody array is useful for the analysis of biomarkers induced by environmental toxic pollutants and can be a powerful tool to study the mechanisms of pollutants in biological samples. © The Korean BioChip Society and Springer 2010. | - |
| dc.format.extent | 6 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | 한국바이오칩학회 | - |
| dc.title | Biomarker analysis of rat livers exposed to different toxic pollutants (VOCs and PAHs) using an antibody array | - |
| dc.type | Article | - |
| dc.publisher.location | 대한민국 | - |
| dc.identifier.doi | 10.1007/s13206-010-4302-x | - |
| dc.identifier.scopusid | 2-s2.0-79959714594 | - |
| dc.identifier.wosid | 000282060300002 | - |
| dc.identifier.bibliographicCitation | BioChip Journal, v.4, no.3, pp 173 - 178 | - |
| dc.citation.title | BioChip Journal | - |
| dc.citation.volume | 4 | - |
| dc.citation.number | 3 | - |
| dc.citation.startPage | 173 | - |
| dc.citation.endPage | 178 | - |
| dc.type.docType | Article | - |
| dc.identifier.kciid | ART001480495 | - |
| dc.description.isOpenAccess | N | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kciCandi | - |
| dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
| dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
| dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
| dc.subject.keywordPlus | VOLATILE ORGANIC-COMPOUNDS | - |
| dc.subject.keywordPlus | GENE-EXPRESSION | - |
| dc.subject.keywordPlus | AIR-POLLUTION | - |
| dc.subject.keywordPlus | PROTEIN | - |
| dc.subject.keywordPlus | ALPHA-2U-GLOBULIN | - |
| dc.subject.keywordPlus | PROTEOCHIP | - |
| dc.subject.keywordPlus | SERUM | - |
| dc.subject.keywordAuthor | Antibody array | - |
| dc.subject.keywordAuthor | Biomarker assay | - |
| dc.subject.keywordAuthor | Environmental pollutants | - |
| dc.subject.keywordAuthor | PAHs | - |
| dc.subject.keywordAuthor | Protein chip | - |
| dc.subject.keywordAuthor | VOCs | - |
| dc.identifier.url | https://link.springer.com/article/10.1007/s13206-010-4302-x | - |
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Related Researcher
- Hwang, Seung Yong
- ERICA 첨단융합대학 (ERICA 분자의약전공)