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Surface modified Fe3O4 nanoparticles as a protein delivery vehicle
- Authors
- Xu, Lixing; Kim, Min-Jung; Kim, Ki-Do; Choa, Young-Ho; Kim, Hee-Taik
- Issue Date
- Oct-2009
- Publisher
- Elsevier BV
- Keywords
- Fe3O4 nanoparticles; PEG; Organosilicon; Protein immobilization
- Citation
- Colloids and Surfaces A: Physicochemical and Engineering Aspects, v.350, no.1-3, pp 8 - 12
- Pages
- 5
- Indexed
- SCIE
SCOPUS
- Journal Title
- Colloids and Surfaces A: Physicochemical and Engineering Aspects
- Volume
- 350
- Number
- 1-3
- Start Page
- 8
- End Page
- 12
- ISSN
- 0927-7757
1873-4359
- Abstract
- We report a one-step synthesis of Fe3O4 nanoparticles coated with PEG. The formation of the Fe3O4 core and the polymer coating took place simultaneously. Furthermore, these nanoparticles were modified with 3-APTES, providing a -NH2 functional group, and applied in the immobilization of lysozyme. In this paper, the modified magnetic nanoparticles acting as a general agent to immobilize proteins are around 10nm in size. The protein immobilization can be adjusted flexibly by changing either the amount of glutaraldehyde or the buffer solution. (C) 2009 Elsevier B.V. All rights reserved.
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Related Researcher
- CHOA, YONG HO
- ERICA 첨단융합대학 (ERICA 신소재·반도체공학전공)