Optimization of Patterned Grooves Micromixer Using the Design of Experiments

Abstract

Mixing independent fluid is of significantly important in microfluidics application, however, is difficult to mix solutions in microchannels. Efficient mixing was also hampered by comparatively slow molecular diffusion process at the micro-scale. In this study, in order to enhance the mixing efficiency, the configuration of patterned grooves micromixer is optimized using an approximate optimization technique. First of all, mixing characteristics analyzed by 3-D Computational Fluid Dynamics. The effective of geometrical parameters on the mixing performance of the staggered herringbone mixer with patterned grooves on the floor are numerical investigated. Groove parameters choose the most effective parameters such as the patterned groove of depth, the patterned groove of length, between grooves distance, and the patterned groove of angle. Design of experiments is applied to the optimization procedure. The optimum micromixer models in parameters region performed to generate using Design of experiments in effective parameters. A mixing index and a pressure drop values calculated at the cross-sections compared each models and proposed optimization of models.