Simultaneous Determination of Bioactive Xanthone Glycosides and Norlignans from Ethanolic Extract of Anemarrhena asphodeloides by Liquid Chromatography
DC Field | Value | Language |
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dc.contributor.author | Islam, M. Nurul | - |
dc.contributor.author | Yoo, Hye Hyun | - |
dc.contributor.author | Lee, Jun | - |
dc.contributor.author | Nam, Joo Won | - |
dc.contributor.author | Seo, Eun Kyoung | - |
dc.contributor.author | Jin, Changbae | - |
dc.contributor.author | Kim, Dong-Hyun | - |
dc.date.accessioned | 2021-06-23T17:03:12Z | - |
dc.date.available | 2021-06-23T17:03:12Z | - |
dc.date.created | 2021-01-21 | - |
dc.date.issued | 2008-11 | - |
dc.identifier.issn | 1060-3271 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/erica/handle/2021.sw.erica/42071 | - |
dc.description.abstract | The rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae) are prescribed as crude drugs in herbal medication for the treatment of various diseases such as diabetes, inflammation, and platelet aggregation inhibition. A simple, sensitive, and precise reversed-phase liquid chromatographic method was developed to study the quantitative determination of 5 bioactive compounds from these rhizomes, namely, neomangiferin, mangiferin, isomangiferin, nyasol, and methylnyasol. Chromatographic analysis was performed on Capcell Pak C-18 column (150 x 4.6 mm, 3 mu m) with a mobile phase consisting of acetonitrile, methanol, and 0.1% formic acid at a flow rate of 1.00 mL/min. Quantitation was performed using a UV-visible detector at 260 nm. The method for the determination of reported medicinal agents was accurate and reproducible. Excellent linear behavior was observed over the investigated concentration range of 2.5-100.0 mu g/mL for neomangiferin; 1.5-60.0 mu g/mL for mangiferin; 0.5-20.0 mu g/mL for nyasol; and 0.2-20.0 mu g/mL for methylnyasol; correlation coefficient > 0.99. The intraday and interday precision over the concentration range of compounds was < 6.6% (relative standard deviation) and accuracy was between 94.9 and 109.3%. This method can be successfully applied for the analysis of medicinal compounds from the ethanolic extract of A. asphodeloides Bunge. | - |
dc.language | 영어 | - |
dc.language.iso | en | - |
dc.publisher | AOAC International | - |
dc.title | Simultaneous Determination of Bioactive Xanthone Glycosides and Norlignans from Ethanolic Extract of Anemarrhena asphodeloides by Liquid Chromatography | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoo, Hye Hyun | - |
dc.identifier.doi | 10.1093/jaoac/91.6.1271 | - |
dc.identifier.scopusid | 2-s2.0-58449134302 | - |
dc.identifier.wosid | 000262118200006 | - |
dc.identifier.bibliographicCitation | Journal of AOAC International, v.91, no.6, pp.1271 - 1277 | - |
dc.relation.isPartOf | Journal of AOAC International | - |
dc.citation.title | Journal of AOAC International | - |
dc.citation.volume | 91 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1271 | - |
dc.citation.endPage | 1277 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | N | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.subject.keywordPlus | TANDEM MASS-SPECTROMETRY | - |
dc.subject.keywordPlus | SWERTIA-MUSSOTII FRANCH | - |
dc.subject.keywordPlus | RAT PLASMA | - |
dc.subject.keywordPlus | CAPILLARY-ELECTROPHORESIS | - |
dc.subject.keywordPlus | ANTIDIABETIC ACTIVITY | - |
dc.subject.keywordPlus | HYPOGLYCEMIC ACTIVITY | - |
dc.subject.keywordPlus | ACTIVE CONSTITUENTS | - |
dc.subject.keywordPlus | MANGIFERIN | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.identifier.url | https://academic.oup.com/jaoac/article/91/6/1271/5656191 | - |
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